Burkitt lymphoma: an unusual location in children, report of a case
DOI:
https://doi.org/10.18203/2349-3291.ijcp20250016Keywords:
BL, Unusual location, Child, LibrevilleAbstract
Burkitt lymphoma (BL) is the most common malignant non-Hodgkin lymphoma in African children. It is a very aggressive lymphoma characterized by a high degree of proliferation. If left untreated, the outcome is quickly fatal. The aim of this work is to present an unusual location of BL. We report the case of an 11-year-old patient with bilateral ocular swelling that has been developing for 2 months associated with swelling spread over the entire body in the form of papules and nodules associated with a deterioration in general condition. A paraclinical assessment, namely orbital magnetic resonance imaging (MRI), revealed an enhanced tumor process in the bilateral upper-lateral eyelid orbital regions and the right supra-nasal paramedian facial soft tissues, diffuse filling of the sinuses, diffuse meningeal enhancement of the peri-brain dura; and histology of a nodule confirmed BL. We reported a case of BL with an unusual ocular and cutaneous presentation, which caused a delay in diagnosis and treatment, thus endangering the vital prognosis of our patient.
Metrics
References
Togo B, Keita M, Medefo D, Traore F, Sidibe T. Burkitt's lymphoma with maxillofacial localization in pediatric settings at Gabriel Touré University Hospital, Bamako, Mali: about 24 cases. Med Trop. 2008;68:600-2.
Oka KH, Djemi EM, Yaude SA, Tuo WTA, Toure I, N'guiessan AA, et al. Epidemiological Aspects of Burkitt's Lymphoma in Children in Bouaké. Health Res Afr. 2024;2(7)11-4.
Mwanda OW, Rochford R, Moormann AM, Macneil A, Whalen C, Wilson ML. Burkitt’s lymphoma in Kenya: geographical, age, gender and ethnic distribution. East Afr Med J. 2004;8(1):S68-77. DOI: https://doi.org/10.4314/eamj.v81i8.9210
Moussaïd Z. Burkitt's lymphoma in children. No: MS 221/22. Final dissertation for obtaining the National Specialty Diploma in Pediatrics. Mohammed V University-Rabat Faculty of Medicine and Pharmacy RABAT. 2022.
El Fahssi M, Khalid S. Childhood Burkitt lymphoma revealed by acute intestinal intussusception. Pan Afri Med J. 2016;24:80. DOI: https://doi.org/10.11604/pamj.2016.24.80.8500
Yao GV, Toutain J, Enoh J, Tre-Yavo M, Dachary D, Couitchere L, et al. Diagnosis of pediatric lymphomas after FNA in Abidjan: evaluation of the reliability of cytological examination in comparison with the study of rearrangement by MYC. Ann Pathol. 2012;32(1):14-8. DOI: https://doi.org/10.1016/j.annpat.2011.08.028
Orem J, Mulumba Y, Algeri S, Bellocco R, Mangen FW, Mbidde EK, et al. Clinical characteristics, treatment and outcome of childhood Burkitt’s lymphoma at the Uganda Cancer Institute. Trans R Soc Trop Med Hyg. 2011;105(12):717-26. DOI: https://doi.org/10.1016/j.trstmh.2011.08.008
San Roman M, Aguilo F, Clapes M, Sheku M, Dawoh P, Mora J, et al. Burkitt’s lymphoma treatment in a rural hospital in Sierra Leone. Trans R Soc Trop Med Hyg. 2013;107(10):653-9. DOI: https://doi.org/10.1093/trstmh/trt069
Stanley CC, Westmoreland KD, Heimlich BJ, El-Mallawany NK, Wasswa P, Mtete I, et al. Outcomes for paediatric Burkitt lymphoma treated with anthracycline-based therapy in Malawi. Br J Haematol. 2016;173(5):705-12. DOI: https://doi.org/10.1111/bjh.13986
Blanc S, Bertrand Y, Lorthois S. Burkitt lymphoma rectal localization. Arch Pediatr. 2002;9(10):1056-8. DOI: https://doi.org/10.1016/S0929-693X(02)00055-6
Zidani S, Izirouel K, Khechfoud H, Djoulane K, Mentri N, Tliba Béjaia S. Burkitt lymphoma in children of cerebral location: about a case. Neurosurgery. 2019;65(2-3):127-8. DOI: https://doi.org/10.1016/j.neuchi.2019.03.070
Banthia V, Albert J, Kacker A. Sporadic Burkitt’s lymphoma of the head and neck in the pediatric population. Int J Pediatr Otorhinolaryngol. 2003;67(1):59-65. DOI: https://doi.org/10.1016/S0165-5876(02)00283-5