Relationship between cerebral blood flow velocities and sociodemographic characteristics of sickle cell anaemia children aged 2-16 years seen at federal teaching hospital Owerri

Authors

  • Ezeuko Lilian Chinasa Department of Paediatrics, Federal Teaching Hospital Owerri Imo State, Nigeria
  • Odunbvun Magdalene Erhieyouvbe Department of Paediatrics, University of Benin Teaching Hospital Benin City, Edo State, Nigeria
  • Ikejiaku Udochikwuka Department of Paediatrics, Federal Teaching Hospital Owerri Imo State, Nigeria
  • Ike Innocent Ifeanyi Department of Paediatrics, Federal Teaching Hospital Owerri Imo State, Nigeria
  • Onwumere Ugonna Ozioma Department of Paediatrics, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria

DOI:

https://doi.org/10.18203/2349-3291.ijcp20250078

Keywords:

Age at diagnosis, Cerebral artery blood flow velocities, Sickle cell anaemia, Socioeconomic status

Abstract

Background: Sickle cell anaemia (SCA) is a chronic haemolytic state associated with recurrent blood transfusions, infections and its attendant complications. The study compared the relationship between cerebral artery blood flow velocities (CBFV) and socio-demographic parameters (age, sex, socioeconomic status and age at diagnosis) of male and female SCA children aged 2-16 years seen at Federal Teaching Hospital Owerri, Imo state.

Methods: Structured questionnaire were used to obtain relevant bio-sociodemographic information’s from SCA children that attended the sickle cell specialist clinic of the hospital between April and September 2023.Later, Transcranial Doppler ultrasound scan was done for them.

Results: A total of 102 subjects were screened within the study period. CBFV decreases with increasing age, 100% of those with abnormal CBFV were aged 2-6 years and 75% females. Majority of children with abnormal CBFV belonged to lower and middle socioeconomic class. Abnormal CBFV was found in 17.6% of subjects

Conclusions: The prevalence of abnormal cerebral blood flow velocity in SCA children is 17.6% and majorily in younger age group. Identification of subjects at risk for a CVA helped in primary prevention by prompt therapy institution.

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References

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Published

2025-01-27

How to Cite

Chinasa, E. L., Erhieyouvbe, O. M., Udochikwuka, I., Ifeanyi, I. I., & Ozioma, O. U. (2025). Relationship between cerebral blood flow velocities and sociodemographic characteristics of sickle cell anaemia children aged 2-16 years seen at federal teaching hospital Owerri. International Journal of Contemporary Pediatrics, 12(2), 147–153. https://doi.org/10.18203/2349-3291.ijcp20250078

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Original Research Articles