Excessive maternal iced-tea intake-reversible cause of premature ductus arteriosus constriction

Vilma Lopes; Joana Pinho; Beatriz Vieira; Maria A. Rangel; Ana Carriço; António Vinhas

doi:10.18203/2349-3291.ijcp20240350

Authors

Vilma Lopes Department of Pediatrics, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Porto, Portugal
Joana Pinho Department of Pediatrics, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Porto, Portugal
Beatriz Vieira Department of Pediatrics, Centro Hospitalar de Póvoa do Varzim e Vila do Conde, Póvoa do Varzim, Portugal
Maria A. Rangel Department of Pediatrics, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Porto, Portugal
Ana Carriço Department of Pediatric Cardiology, Centro Hospitalar de Vila Nova de Gaia e Espinho, Vila Nova de Gaia, Portugal
António Vinhas Neonatal Intensive Care Unit, Pediatric Department, Centro Hospitalar de Vila Nova de Gaia e Espinho, Vila Nova de Gaia, Portugal

DOI:

https://doi.org/10.18203/2349-3291.ijcp20240350

Keywords:

Ductus arteriosus, Polyphenols, Gestation

Abstract

Premature ductus arteriosus constriction is a rare entity associated with high neonatal morbidity and mortality. Most cases are idiopathic, with the major known cause being maternal use of nonsteroidal anti-inflammatory drugs. Polyphenol-rich foods have been proven to have a deleterious fetal hemodynamic effect that can lead to premature ductal constriction. We report a case of a neonate diagnosed with premature ductal arteriosus closure, whose only risk factor was an excessive maternal intake of commercial iced-tea during pregnancy. The authors aim to raise awareness to the impact of polyphenol-rich food consumption on ductus arteriosus, since maternal dietary advice can have a major preventive role. Furthermore, a timely diagnosis and intervention can prevent significant morbidity and mortality.

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