DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20172516

Immediate outcome and risk factors determining the outcome of status epilepticus in children attending tertiary care centre

Murali Thandavarayan, Sureshkumar Ramaswamy, Priyadarsini Bose, Sivaraman Thirumalaikumarasamy

Abstract


Background: Status epilepticus (SE) is a paediatric and neurological medical emergency, continuous seizure lasting more than 30 min, or two or more seizures without full recovery of consciousness between any of them. Determination of immediate outcome of SE in children in a tertiary care hospital and to identify the risk factors influencing the outcome was the objectives of the present study.

Methods: A study was conducted in Dept of Pediatrics, Tirunelveli Medical College Hospital among the children from 1 month to12 years of age, who had admitted for SE in hospital’s pediatric causality from October 2009 to October 2010 were selected for the study.

Results: Out of 92 patients, total 87 patients completed the study and out of those 74 have recovered and 13 have died. The risk factors significantly affecting the outcome were hypoxia at the time of arrival, decompensated shock, respiratory failure requiring intubation and acidosis.

Conclusions: Proper prehospital therapy, early referral, proper care while transporting, anticipitating risk factors involved, and protocol based approach uniformly at all hospital can reduce the mortality due to status epilepticus in children. 


Keywords


Children, Outcome, Risk factors, Status epilepticus

Full Text:

PDF

References


Cherian A, Thomas SV. Status epilepticus. Ann Indian Acad Neurol. 2009;12(3):140-53.

Morton LD, Pellock JM. Status epilepticus. Available: https://clinicalgate.com/status-epilepticus-4. Accessed on 05 February 2017.

Chin RF, Neville BG, Scott RC. A systematic review of the epidemiology of status epilepticus. Eur J Neurol. 2004;11(12):800-10.

Working Group on Status Epilepticus. Treatment of CSE: recommendations of Epilepsy Foundation of America’s working group of SE. JAMA. 1993;270:854-9.

David JJ, Tasker RC. The management of acute epileptic seizures and status epilepticus. Recent advances in pediatrics. 2001;19:1-16.

Hanhan VA, Fiallos MR. Status Epilepticus. Ped clinic of North America. 2001;48:683-94.

Maytal J, Shinner S, Moshe SL, Alvarez LA. Low morbidity and mortality of SE in children. Pediatrics. 1989;83(3):323-31.

Eriksson K. Treatment delay and the risk of prolonged status epilepticus. Lancet. 2006;368(9531):222-9.

Garzon E, Fernandes RM, Sakamoto AC. Analysis of clinical characteristics and risk factors for mortality in human status epilepticus. Seizure. 2003;12(6):337-45.

Mah JK, Mah MW. King Khalid national gaurd hospital, Jeddah, Kingdom of SA. Padiatric SE perspective. Pediatric neurol. 1999:20(5):364-9.

Murthy JM, Yangala R. Nizams institute of medical science, Hydrabad. Seizure. 1999;8(3):162-5.

Alldredge BK, Wall DB, Ferriero DM. Effect of prehospital treatment on the outcome of status epilepticus in children. Pediatr Neurol. 1995;12(3):213-6.

Gulati S, Kalra V, Sridhar MR. Status epilepticus in Indian children in a tertiary care center. Indian J Pediatr. 2005;72(2):105-8.

Kwong KL, Chang K, Lam SY. Objective. Features predicting adverse outcomes of status epilepticus in childhood. Hong Kong Med J. 2004;10:156-9.