Association of serum vitamin D levels and transient tachypnea of newborn: a case control study


  • Gurmeet Singh Department of Pediatrics, Sh. Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Reena Sood Department of Obstetrics and Gynecology, Sh. Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Gursharan Singh Narang Department of Pediatrics, Sh. Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Harnoorjit Kaur Brar Department of Pediatrics, Sh. Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India
  • Amanjeet Kaur Bagga Department of Pediatrics, Sh. Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India



Lower segment cesarean section (LSCS), Respiratory distress, Term newborns, Transient tachypnea of newborn (TTN), Vitamin D


Background: Transient tachypnea of newborn (TTN) is a common cause of respiratory distress in newborns with estimated incidence of 1-2% of all newborns. Although a self-limiting transient condition but it may cause severe morbidities. This study was conducted to find association of serum vitamin D levels in neonates who develop TTN as compared to normal healthy neonates.

Methods: With thorough history with structured questionnaire and lab tests, serum vitamin D levels of 45 neonates who develop TTN were compared with 56 healthy neonates in control group.

Results: Out of 45 neonates who develop TTN 39(86.7%) were deficient in vitamin D as compared to control group where 33(58.9%) out of 56 healthy neonates were deficient in vitamin D.

Conclusions: Lower vitamin D levels at birth in term neonates is associated with increased risk of developing TTN and vitamin D may have a role in its pathogenesis. 


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Original Research Articles