Disseminated tuberculosis in an immunocompetent adolescent girl presenting without fever: a master clinical conundrum

Authors

  • Archana Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
  • Samiksha Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
  • Tushar B. Jagzape Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India https://orcid.org/0000-0002-4462-4494
  • Tripty H. Singh Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
  • Anil K. Goel Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20261148

Keywords:

Disseminated tuberculosis, Immunocompetent child, Spinal intramedullary tuberculoma, Atypical presentation of TB

Abstract

Disseminated tuberculosis (TB) in immunocompetent child is rare and poses a diagnostic challenge, especially in the absence of typical systemic features. We present a 14-year-old previously healthy girl with no history of fever, cough, or weight loss, who developed progressive lower limb weakness, constipation, and urinary retention. Imaging revealed spinal intramedullary tuberculoma, multiple brain tuberculomas, and pulmonary involvement. Microbiological confirmation was achieved via bronchoscopy. This case emphasizes the importance of high clinical suspicion, early imaging, and microbiological workup in atypical presentations of TB.

References

Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: pathogenesis and clinical aspects. Clin Microbiol Rev. 2008;21(2):243-61.

Sharma SK, Mohan A. Central nervous system tuberculosis. Indian J Med Res. 2020;151(6):493-505.

Jaiswal AK, Jaiswal S, Kumar S, Gupta RK, Sharma MS, Sharma BS. Intramedullary spinal cord tuberculoma: a series of 14 cases. Neurol India. 2006;54(4):390-2.

Kalita J, Misra UK. Tuberculous meningitis: diagnosis and management. Ann Indian Acad Neurol. 2019;22(3):250-9.

Thwaites GE, Fisher M, Hemingway C, Scott G, Solomon T, Innes J. British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system. J Infect. 2009;59(3):167-87.

Vidyalaxmi K, Shankar SK, Mahadevan A. Pathology of tuberculosis of the central nervous system. Neurol India. 2009;57(6):681-8.

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Published

2026-04-23

How to Cite

Archana, Samiksha, Jagzape, T. B., Singh, T. H., & Goel, A. K. (2026). Disseminated tuberculosis in an immunocompetent adolescent girl presenting without fever: a master clinical conundrum . International Journal of Contemporary Pediatrics, 13(5), 784–787. https://doi.org/10.18203/2349-3291.ijcp20261148

Issue

Section

Case Reports