Laboratory-confirmed measles in a 5-month-old infant: a case report highlighting early susceptibility and public health implications

Authors

  • Rama Kaja Department of Paediatrics, Vijay Marie Hospital, Telangana, India
  • Ansar M. Hussain Department of Paediatrics, Vijay Marie Hospital, Telangana, India
  • Abitha Rathinam Muthu Department of Paediatrics, Vijay Marie Hospital, Telangana, India
  • Surendranath M. Department of Paediatrics, Vijay Marie Hospital, Telangana, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20260830

Keywords:

Measles, Infant, Maternal immunity, Vitamin A, Vaccine-preventable disease, Public health

Abstract

Measles disease is caused by the measles virus, a negative-sense, single-stranded, lipid-enveloped RNA virus of family Paramyxoviridae and genus morbillivirus. Measles in infants under the age of eligibility for Measles containing vaccination (MCV) remains a public health concern in India. We report a laboratory confirmed case of measles in a 5-month-old infant who presented with fever, cough and coryza. Clinical findings, laboratory investigations, and hospital courses were documented. Diagnosis was confirmed by detection of measles-specific immunoglobulin M (IgM) antibodies. This case highlights the vulnerability of infants below 6 months of age to measles despite presumed maternal immunity and the need for strengthened measles control strategies, high community vaccination coverage, and consideration of early preventive measures during outbreaks to protect young infants.

References

Kliegman RM, St Geme JW III, Blum NJ, Shah SS, Tasker RC, Wilson KM. Nelson Textbook of Pediatrics. Philadelphia: Elsevier; 2023. Available at: https://shop.elsevier.com/books/nelson-textbook-of-pediatrics-2-volume-set/kliegman/978-0-323-88305-4?. Accessed on 21 January 2026.

World Health Organization. Measles vaccines: WHO position paper. Wkly Epidemiol Rec. 2017;92(17):205-28. Available at: https://www. who.int/publications/i/item/whower9217-205-227?. Accessed on 21 January 2026.

Mathew JL, Wagner AL, Ratho RK, Patel PN, Suri V, Bharti B, et al. Maternally transmitted anti-measles antibodies and susceptibility to disease among infants in Chandigarh, India: A prospective birth cohort study. PLoS One. 2023;18(10):e0287110.

Szenborn L, Tischer A, Pejcz J, Rudkowski Z, Wójcik M. Passive acquired immunity against measles in infants born to naturally infected and vaccinated mothers. Med Sci Monit. 2003;9(12):CR541-6.

Ong DS, von Mollendorf C, Mulholland K, Do LAH. Measles seroprevalence in infants under 9 months of age in low- and middle-income countries: A systematic review and meta-analysis. J Infect Dis. 2025;232(2):316-26.

D’Souza RM, D’Souza R. Vitamin A for the treatment of children with measles—A systematic review. J Trop Pediatr. 2002;48(6):323-7.

World Health Organization. Guideline: Vitamin A supplementation in infants and children 6–59 months of age. Geneva: WHO; 2011. Available at : https://www.who.int/publications/i/item/9789241501767. Accessed on 21 January 2026.

Indian Academy of Pediatrics. Measles and Rubella vaccination guidelines. Indian Pediatr. 2020. Available at: https://www.indianpediatrics.net/ jan2021/jan-44-53.htm. Accessed on 21 January 2026.

Chan WM, Lee SH, Kwan MYW, Chow CB, Leung CW. Modified clinical manifestations of measles in young infants: Ten years’ experience in a tertiary referral center. Hong Kong J Paediatr. 2010;15:126-31.

Downloads

Published

2026-03-25

How to Cite

Kaja, R., Hussain, A. M., Muthu, A. R., & M., S. (2026). Laboratory-confirmed measles in a 5-month-old infant: a case report highlighting early susceptibility and public health implications . International Journal of Contemporary Pediatrics, 13(4), 660–662. https://doi.org/10.18203/2349-3291.ijcp20260830

Issue

Section

Case Reports