Neonatal epidermolysis bullosa simplex: a mechanobullous skin fragility disease

Shireen Ahmed; Baraturam Bhaisara; Dhara Shah; Abhay Trivedi

doi:10.18203/2349-3291.ijcp20260828

Authors

Shireen Ahmed Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India
Baraturam Bhaisara Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India
Dhara Shah Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India
Abhay Trivedi Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20260828

Keywords:

Epidermolysis bullosa, Newborn, Inherited skin disorder, Skin blistering, Skin fragility, Genodermatosis

Abstract

Epidermolysis bullosa (EB) is a group of hereditary skin blistering disorders characterised by skin fragility and mechanically induced blistering. We present a case of a full-term female neonate with widespread, fragile blisters and erosions at birth, prompting early suspicion of EB. Rapid dermatological evaluation and immunofluorescence antigen mapping confirmed EB simplex (EBS), allowing prompt intervention. Early parental counselling plays a crucial role in ensuring confidence in home care. After six weeks, the mother managed feeding and wound care independently. This case highlights the importance of recognising neonatal skin fragility early, facilitating timely diagnosis and intervention to minimise complications and improve long-term outcomes in infants with EB.

Author Biographies

Shireen Ahmed, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India

Junior Redident, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital

Baraturam Bhaisara, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India

Additional Professor, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital

Dhara Shah, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital, Mumbai, Maharashtra, India

Assistant Professor, Department of Pediatrics, HBT Medical College and Dr R.N. Cooper Hospital Municipal General Hospital

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