Psychomotor development at 9 months of age in infants with perinatal asphyxia at the Mother and Child University Hospital of Libreville (Gabon) in 2023

Aude M. L. Mikolo; Raissa K. Maniaga; Gessica M. N. Matoumba; Jules Tsafack; Edmée M. M. Nkama; Morgane Mboungani; Eliane K. Kamgaing; Simon Ategbo

doi:10.18203/2349-3291.ijcp20260393

Authors

Aude M. L. Mikolo University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon https://orcid.org/0009-0006-6722-0042
Raissa K. Maniaga University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon
Gessica M. N. Matoumba University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon
Jules Tsafack Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon
Edmée M. M. Nkama University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon
Morgane Mboungani University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon
Eliane K. Kamgaing University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon https://orcid.org/0000-0002-4594-2582
Simon Ategbo University of Health Sciences of Libreville, Mother and Child University Hospital, Jeanne Ebori Foundation of Libreville, Gabon

DOI:

https://doi.org/10.18203/2349-3291.ijcp20260393

Keywords:

Asphyxia, Hypoxia, Hypothermia, Encephalopathy, Libreville

Abstract

Background: Perinatal asphyxia (PNA) is a common condition in neonatology. Objective of the study was to describe the short- and medium-term outcome of newborns presenting with PNA at the Centre Hospitalier Universitaire Mère-Enfant Fondation Jeanne Ebori (CHUME-FJE) in 2022.

Methods: A prospective longitudinal and analytical study was conducted over a 16-month period. Newborns were included, regardless of gestational age, had presented with PNA. The statistical significance threshold was set at p<0.05.

Results: 96/464 newborns hospitalized for PNA (20.7%). The sex ratio was 1.26. The mean resuscitation time was 9.1±7.1 min. Neurological complications accounted for 73.3% (n=63), with an AEI classified as Sarnat II (27.0%) and Sarnat III (22.2%). The mean hospital stay was 12.6 days. The overall death rate was 32.6%. During the course of the study, 50.0% of infants recovered to normal weight for their age at 9 months and a proportion of 7.7% presented with PML developmental delay and 11.5% with PCVM taking into account the corrected age for preterm newborns.

Conclusion: APN remains a public health problem in sub-Saharan countries with high neonatal mortality and long-term neurodevelopmental sequelae. Prevention of this condition relies on better monitoring of pregnancy and delivery and a training program for healthcare personnel in newborn resuscitation in the delivery room.

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