Cataract in childhood diabetes: more than what meets the eye

Authors

  • Simran Syal Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India
  • Anil K. Goel Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India
  • Tushar B. Jagzape Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India
  • Lubna Khan Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India
  • Mohit D. Jaiswal Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India
  • Charandeep Singh Gandhoke Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20254193

Keywords:

Type 1 diabetes mellitus, Cataract, Mauriac syndrome, Ophthalmological screening

Abstract

Diabetic cataract is a rare but sight threatening complication in children. Two cases of paediatric diabetic cataract are described, one is in a six-year-old girl with diabetes duration of four years with systemic features of poorly controlled T1DM in the form of Mauriac syndrome and another is of a 13 years 6 months old boy with relatively recent diabetes diagnosis 6 months back, both presenting with visually significant cataracts. Regular ophthalmological screening examinations in patients with T1DM starting right from the time of diagnosis are essential to pick up and treat this complication early for best results.

Metrics

Metrics Loading ...

References

Libman I, Haynes A, Lyons S, Pradeep P, Rwagasor E, Tung JY, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescents. Pediatr Diabetes. 2022;23(8):1160-74. DOI: https://doi.org/10.1111/pedi.13454

Lu WL, Shen PC, Lee CH, Su YT, Chen LM. High Risk of Early Cataracts in Young Type 1 Diabetes Group: A Nationwide Cohort Study. Int J Endocrinol. 2020;2020:8160256. DOI: https://doi.org/10.1155/2020/8160256

Šimunović M, Paradžik M, Škrabić R, Unić I, Bućan K, Škrabić V. Cataract as Early Ocular Complication in Children and Adolescents with Type 1 Diabetes Mellitus. Int J Endocrinol. 2018;2018:6763586. DOI: https://doi.org/10.1155/2018/6763586

Wilson ME Jr, Levin AV, Trivedi RH, Kruger SJ, Elliott LA, Ainsworth JR, et al. Cataract associated with type-1 diabetes mellitus in the pediatric population. J AAPOS. 2007;11(2):162-5. DOI: https://doi.org/10.1016/j.jaapos.2005.10.005

Costagliola C, Dell'Omo R, Prisco F, Iafusco D, Landolfo F, Parmeggiani F. Bilateral isolated acute cataracts in three newly diagnosed insulin dependent diabetes mellitus young patients. Diabetes Res Clin Pract. 2007;76(2):313-5. DOI: https://doi.org/10.1016/j.diabres.2006.08.010

Kador PF, Akagi Y, Kinoshita JH. Diabetic cataracts in animal models: prevention and reversibility with aldose reductase inhibitors. Diabet Med. 1985;2(3):194-6. DOI: https://doi.org/10.1111/j.1464-5491.1985.tb00634.x

Su S, Leng F, Guan L, Zhang L, Ge J, Wang C, et al. Differential proteomic analyses of cataracts from rat models of type 1 and 2 diabetes. Invest Ophthalmol Vis Sci. 2014;55(12):7848-61. DOI: https://doi.org/10.1167/iovs.14-15175

Papadimitriou DT, Bothou C, Skarmoutsos F, Alexandrides TK, Papaevangelou V, Papadimitriou A. The autoimmune hypothesis for acute bilateral cataract in type 1 diabetes. Diabetes Metab. 2016;42(5):386-7. DOI: https://doi.org/10.1016/j.diabet.2016.04.006

American Diabetes Association; 11. Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes−2020. Diabetes Care. 2020;43:S135–51. DOI: https://doi.org/10.2337/dc20-S011

Lueder GT, Silverstein J. American Academy of Pediatrics Section on Ophthalmology and Section on Endocrinology. Screening for retinopathy in the pediatric patient with type 1 diabetes mellitus. Pediatrics. 2005;116(1):270-3. DOI: https://doi.org/10.1542/peds.2005-0875

Bjornstad P, Dart A, Donaghue KC, Dost A, Feldman EL, Tan GS, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Microvascular and macrovascular complications in children and adolescents with diabetes. Pediatr Diabetes. 2022;23(8):1432-50. DOI: https://doi.org/10.1111/pedi.13444

Downloads

Published

2025-12-24

How to Cite

Syal, S., Goel, A. K., Jagzape, T. B., Khan, L., Jaiswal, M. D., & Gandhoke, C. S. (2025). Cataract in childhood diabetes: more than what meets the eye. International Journal of Contemporary Pediatrics, 13(1), 95–98. https://doi.org/10.18203/2349-3291.ijcp20254193

Issue

Section

Case Reports