A silent invader: disseminated tuberculosis presenting with hepatic abscesses in early childhood

Keerthana Reddy; Mithila Das Mazumder; Divyasree Chimata; Vindya Reddy

doi:10.18203/2349-3291.ijcp20260107

Authors

Keerthana Reddy Department of Paediatrics, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India https://orcid.org/0009-0003-5290-9451
Mithila Das Mazumder Department of Paediatrics, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India https://orcid.org/0009-0000-5801-2205
Divyasree Chimata Department of Paediatrics, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India https://orcid.org/0000-0001-9274-3917
Vindya Reddy Department of Paediatrics, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India https://orcid.org/0009-0001-7258-7029

DOI:

https://doi.org/10.18203/2349-3291.ijcp20260107

Keywords:

Disseminated tuberculosis, Hepatic abscess, Infant, GeneXpert, Antitubercular therapy

Abstract

Disseminated tuberculosis (TB) is a severe and potentially fatal form of Mycobacterium tuberculosis infection caused by haematogenous spread to two or more non-contiguous organs. Diagnosis is often challenging due to its non-specific clinical presentation and resemblance to other systemic infections. We describe a 9-month-old partially immunized male infant presenting with recurrent vomiting, fever, and poor feeding. Imaging revealed hepatic abscesses and pulmonary nodules. Cerebrospinal fluid GeneXpert detected Mycobacterium tuberculosis. The child was managed with first-line antitubercular therapy, supportive care, and nutritional rehabilitation, with marked clinical improvement. Disseminated tuberculosis in infancy is uncommon but carries high morbidity and mortality. Early clinical suspicion, prompt diagnosis, and timely initiation of therapy are crucial for favourable outcomes.

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