From awareness to accountability: strengthening pediatric antibiotic stewardship in low-resource outpatient setting
DOI:
https://doi.org/10.18203/2349-3291.ijcp20260117Keywords:
Antibiotic stewardship, Pediatrics, Antimicrobial resistance, AuditAbstract
In pediatric outpatient departments, antibiotic prescriptions are frequently empirical and often used for self-limiting viral illnesses, fueling antimicrobial resistance (AMR). While awareness programs have improved knowledge among clinicians and caregivers, sustainable behavioral change remains limited without accountability mechanisms. This letter highlights the critical role of pediatric antimicrobial stewardship programs (ASPs), emphasizing audit-feedback interventions that have shown up to a 23% reduction in unnecessary antibiotic initiation and a 17% reduction in broad-spectrum antibiotic selection. In low-resource outpatient settings, the lack of point-of-care diagnostics perpetuates empirical prescribing. Integrating affordable diagnostic tools, enforcing stewardship policies, and adopting the WHO AWaRe framework within regional healthcare systems can strengthen accountability and optimize antibiotic use in children.
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References
Duan L, Liu C, Wang D, Lin R, Qian P, Zhang X, et al. The vicious cycle of the public's irrational use of antibiotics for upper respiratory tract infections: A mixed methods systematic review. Front Public Health. 2022;10:985188. DOI: https://doi.org/10.3389/fpubh.2022.985188
Maarouf L, Amin M, Evans BA, Abouelfetouh A. Knowledge, attitudes and behaviour of Egyptians towards antibiotic use in the community: can we do better? Antimicrob Resist Infect Control. 2023;12(1):50. DOI: https://doi.org/10.1186/s13756-023-01249-5
Donà D, Barbieri E, Daverio M, Lundin R, Giaquinto C, Zaoutis T, et al. Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review. Antimicrob Resist Infect Control. 2020;9(1):3. DOI: https://doi.org/10.1186/s13756-019-0659-3
Xu AXT, Brown K, Schwartz KL, Aghlmandi S, Alderson S, Brehaut JC, et al. Audit and Feedback Interventions for Antibiotic Prescribing in Primary Care: A Systematic Review and Meta-analysis. Clin Infect Dis. 2025;80(2):253-62. DOI: https://doi.org/10.1093/cid/ciae604
Tolley A, Bansal A, Murerwa R, Dicks JH. Cost-effectiveness of point-of-care diagnostics for AMR: a systematic review. J Antimicrob Chemother. 2024;79(6)1248-69. DOI: https://doi.org/10.1093/jac/dkae067
Wesangula E, Chizimu JY, Mapunjo S, Mudenda S, Seni J, Mitambo C, et al. A Regional Approach to Strengthening the Implementation of Sustainable Antimicrobial Stewardship Programs in Five Countries in East, Central, and Southern Africa. Antibiotics (Basel). 2025;14(3):266. DOI: https://doi.org/10.3390/antibiotics14030266