Unmasking the unexpected: a rare case report of B-acute lymphoblastic leukemia

Authors

  • Jyoti Ahuja Department of Paediatrics, R. N. T. Medical College, Udaipur, Rajasthan, India https://orcid.org/0009-0004-6871-7400
  • Vivek Arora Department of Paediatrics, R. N. T. Medical College, Udaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20260417

Keywords:

Acute lymphoblastic leukemia, Paraplegia, Backache

Abstract

Acute lymphoblastic leukemia (ALL) is a neoplastic proliferation of immature hematopoietic cells, commonly presenting with anaemia, thrombocytopenia, neutropenia, or hepatosplenomegaly. Paraplegia as the initial manifestation is extremely rare. We report a 6-year-old girl presenting with backache and sudden paraplegia. MRI revealed a thoracic epidural mass (D1-D6). Tumor excision and laminectomy were performed, and histopathology confirmed B-cell ALL. This case highlights the importance of considering leukemia in children with acute spinal cord compression.

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References

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Kataoka A, Shimizu K, Matsumoto T, Shintaku N, Okuno T, Takahashi Y, et al. Epidural spinal cord compression as an initial symptom in childhood acute lymphoblastic leukemia: rapid decompression by local irradiation and systemic chemotherapy. Pediatr Hematol Oncol. 1995;12(2):179-84. DOI: https://doi.org/10.3109/08880019509029552

Yang L, Luo S, Ye P. Extramedullary Relapse of Acute B-Lymphoblastic Leukemia Leading to Paraplegia in a Child with Down Syndrome. Clin Lab. 2025;71:4. DOI: https://doi.org/10.7754/Clin.Lab.2024.241052

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Published

2026-02-21

How to Cite

Ahuja, J., & Arora, V. (2026). Unmasking the unexpected: a rare case report of B-acute lymphoblastic leukemia. International Journal of Contemporary Pediatrics, 13(3), 512–514. https://doi.org/10.18203/2349-3291.ijcp20260417

Issue

Section

Case Reports