The effect of hypovitaminosis D in mother on newborn babies in North India: a case series

Authors

  • Tanya Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
  • Agam Rai Big Data Analytics, Wroclaw University of Science and Technology, Wroclaw, Poland
  • Jasmine Department of Medicine, Aam Adami Clinic, Jalandhar, Punjab, India
  • Sunil S. Bains Punjab Institute of Medical Sciences, Jalandhar, Punjab, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20252226

Keywords:

Hypovitaminosis, Hypocalcemia in newborn, Seizures, Multiple fractures, Refractory hypocalcemia, Case report

Abstract

Vitamin D deficiency is a widespread concern during pregnancy across the globe. This issue can be linked to various factors, including lifestyle changes, reduced sunlight exposure, the application of sunscreen, inadequate dietary intake of vitamin D, and a lack of vitamin D supplementation during the antenatal period. Such a deficiency can affect newborns, and the symptoms can vary, complicating the diagnostic process. Only limited reports have been published on the effect of hypovitaminosis D in mothers on newborn children. We present a case series of three newborns from India who were influenced by the mother’s hypovitaminosis D. In the first case the baby suffered from multiple rib fractures. In the second case the baby developed seizures and in the third case the baby was asymptomatic but suffered from refractory hypocalcemia. Due to increasing rates of vitamin D deficiency in pregnancy, a suspicion should be kept for diagnosis of hypovitaminosis and hypocalcemia in newborn with unexplained presentations.

Metrics

Metrics Loading ...

Author Biography

Agam Rai, Big Data Analytics, Wroclaw University of Science and Technology, Wroclaw, Poland

Department of Fundamental Problems of Technology

MS, Big Data Analytics

Wroctaw University of Science and Technology, Wroclaw, Poland

References

Sizar O, Khare S, Goyal A, Givler A. Vitamin D deficiency. 2023.

Dragomir RE, Toader DO, Gheoca Mutu DE, Dogaru IA, Răducu L. Consequences of maternal vitamin D deficiency on newborn health. Life. 2024;14(6):714. DOI: https://doi.org/10.3390/life14060714

Sonowal R, Das M, Deka BP, Das P. Effects of maternal vitamin D deficiency on the newborn: a cohort study. Indian J Neonatal Med Res. 2021;9(2):2319. DOI: https://doi.org/10.7860/IJNMR/2021/47986.2318

Karras SN, Fakhoury H, Muscogiuri G, Grant WB, van den Ouweland JM, Colao AM, Kotsa K. Maternal vitamin D levels during pregnancy and neonatal health: evidence to date and clinical implications. Ther Adv Musculoskelet Dis. 2016;8(4):124-35. DOI: https://doi.org/10.1177/1759720X16656810

Roomi MA, Farooq A, Ullah E, Lone KP. Hypovitaminosis D and its association with lifestyle factors. Pak J Med Sci. 2015;31:1236-40. DOI: https://doi.org/10.12669/pjms.315.7196

Mansur JL, Oliveri B, Giacoia E, Fusaro D, Costanzo PR. Vitamin D: before, during and after pregnancy: effect on neonates and children. Nutrients. 2022;14(9):1900. DOI: https://doi.org/10.3390/nu14091900

Mallick AK, Yadav RK, Sannalli K, et al. Maternal hypovitaminosis D presenting as late-onset hypocalcemic seizure in a term neonate: a case report. Egypt Pediatric Association Gaz. 2023;71:15. DOI: https://doi.org/10.1186/s43054-023-00164-z

8Pandya A, Aldouri A, Pandya N, Bhaduri B. A case series of vitamin D deficiency in mothers affecting their infants. Infant J. 2010;6(6):196-200.

Camadoo L, Tibbott R, Isaza F. Maternal vitamin D deficiency associated with neonatal hypocalcaemic convulsions. Nutr J. 2007;6:23. DOI: https://doi.org/10.1186/1475-2891-6-23

Al Emadi S, Hammoudeh M. Vitamin D study in pregnant women and their babies. Qatar Med J. 2013;2013(1):32-7. DOI: https://doi.org/10.5339/qmj.2013.7

Downloads

Published

2025-07-24

How to Cite

Tanya, Rai, A., Jasmine, & Bains, S. S. (2025). The effect of hypovitaminosis D in mother on newborn babies in North India: a case series. International Journal of Contemporary Pediatrics, 12(8), 1414–1417. https://doi.org/10.18203/2349-3291.ijcp20252226

Issue

Section

Case Series