Psychiatric crisis to abdominal tuberculosis
DOI:
https://doi.org/10.18203/2349-3291.ijcp20251889Keywords:
Abdominal tuberculosis, Adolescent depression, Suicidal attempt, Ileocecal tuberculosis, GeneXpert, Drug induced liver injury, Multidisciplinary careAbstract
We report a case of a 15-year-old female presenting with alprazolam overdose, psychiatric symptoms, and subsequent diagnosis of ileocecal tuberculosis (TB). Initial management addressed acute overdose and psychiatric illness, followed by identification of TB through imaging, colonoscopy, and histopathological confirmation. Drug-induced liver injury (DILI) complicated first-line anti-TB therapy, necessitating a modified regimen. This case highlights the diagnostic challenges in patients with overlapping psychiatric and systemic presentations, underscoring the critical role of thorough clinical and diagnostic evaluation in adolescents presenting with psychiatric symptoms and gastrointestinal complaints and the importance of monitoring for hepatotoxicity during ATT.
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Kerfoot M. Managing suicidal behaviour in adolescents. Psychiatry. 2009;8(7):252-6. DOI: https://doi.org/10.1016/j.mppsy.2009.04.010
Ewing ES, Hunt QA, Singer JB, Diamond G, Winley D. Youth Suicide: Risk, Prevention, and Treatment. The Handbook of Systemic Family Therapy. 2020;2:343-67. DOI: https://doi.org/10.1002/9781119438519.ch47
World Health Organization. Global Tuberculosis Report 2023. Geneva: World Health Organization. 2023.
Ladumor H, Al-Mohannadi S, Ameerudeen FS, Ladumor S, Fadl S. TB or not TB: A comprehensive review of imaging manifestations of abdominal tuberculosis and its mimics. Clin Imaging. 2021;76:130-43. DOI: https://doi.org/10.1016/j.clinimag.2021.02.012
Patel V, Flisher AJ, Hetrick S, McGorry P. Mental health of young people: a global public-health challenge. The lancet. 2007;369(9569):1302-13. DOI: https://doi.org/10.1016/S0140-6736(07)60368-7
Sharma MP, Bhatia V. Abdominal tuberculosis. Indian J Med Res. 2004;120:305-15.
Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, et al. Differentiating Crohn’s disease from intestinal tuberculosis. World J Gastroenterol. 2019;25(4):418. DOI: https://doi.org/10.3748/wjg.v25.i4.418
Elbrolosy AM, El Helbawy RH, Mansour OM, Latif RA. Diagnostic utility of GeneXpert MTB/RIF assay versus conventional methods for diagnosis of pulmonary and extra-pulmonary tuberculosis. BMC Microbiol. 2021;21:1-0. DOI: https://doi.org/10.1186/s12866-021-02210-5
Muangsomboon K, Thepchana C, Thiravit P, Muangsomboon S. Computerized Tomography Features of Abdominal Tuberculosis. Siriraj Med J. 2014;66(3):10.
Moka P, Ahuja V, Makharia GK. Endoscopic features of gastrointestinal tuberculosis and Crohn’s disease. J Digestive Endoscopy. 2017;8(01):01-11. DOI: https://doi.org/10.4103/jde.jde_48_16
Saminathan S, Panse D, Krishnappa P. Current Trend in Diagnosis of Tuberculosis Infection. Int J Collaborative Res Internal Med Publ Health. 2019;11(2):898-903.
Luca M, Perlman-Arrow A, Bastos ML, Menzies D. A Systematic Review and Meta-Analysis of Tuberculous Preventative Therapy Adverse Events. Clin Infect Dis. 2023;77(2):287-94. DOI: https://doi.org/10.1093/cid/ciad246
Wang D, Cai XL, Lin X, Zheng J, Wu YL, Peng XE. Hepatoprotective drugs for prevention of liver injury resulting from anti-tuberculosis treatment: a meta-analysis of cohort studies. Infectious Med. 2022;1(3):154-62. DOI: https://doi.org/10.1016/j.imj.2022.07.003
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