Medical mimicry: abdominal tuberculosis presenting as surgical emergency
DOI:
https://doi.org/10.18203/2349-3291.ijcp20252228Keywords:
Abdominal pain, TB, GeneXpertAbstract
Abdominal tuberculosis is a relatively uncommon but important differential diagnosis in patients presenting with abdominal symptoms, especially in regions with high TB prevalence. This case report describes an 11-years-old boy who presented with abdominal and scrotal swelling, along with intermittent fever, mimicking a surgical emergency. An initial clinical impression of ruptured appendicitis led to an exploratory laparotomy, which revealed copious serous fluid and widespread pale, firm seedlings throughout the peritoneal cavity. Histological examination of omental tissue showed chronic necrotizing granulomatous inflammation suggestive of tuberculosis. Despite inconclusive GeneXpert and microbiological findings, the clinical picture prompted a therapeutic trial of anti-TB medications. The patient responded remarkably, with complete resolution of symptoms and significant weight gain. This case underscores the diagnostic difficulty posed by abdominal TB and highlights the potential role of empirical anti-TB therapy in appropriate clinical contexts when diagnostic tools are limited or yield inconclusive results.
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References
Olaleye SA, Balogun OS, Adusei-Mensah F. Bibliometric structured review of tuberculosis in Nigeria. Afr Health Sci. 2023;23:139–60. DOI: https://doi.org/10.4314/ahs.v23i2.16
Alex-Hart BA, Paul NI. Pattern and outcome of childhood tuberculosis seen at the university of port Harcourt teaching hospital, Nigeria. J Tuberc Res. 2019;07:170–83. DOI: https://doi.org/10.4236/jtr.2019.73017
Mado S, Isa A, Abubakar U. Spectrum of tuberculosis in children at Federal Medical Centre, Gusau, Zamfara State, Northwestern Nigeria. Sahel Med J. 2017;20:8. DOI: https://doi.org/10.4103/1118-8561.204330
Ip O, Umo OT D, Ei A. Ileocaecal tuberculosis in A Nigerian child: A case report. Acta Sci Paediatr. 2020;3:1–5. DOI: https://doi.org/10.31080/ASPE.2020.03.0228
Dauda MM, Ahmed A, Okpapi JU. Abdominal tuberculosis in surgical practice in northern Nigeria. Niger J Med. 2010;19:415–8. DOI: https://doi.org/10.4314/njm.v19i4.61966
Ohanaka CE, Egbagbe EE. Adult abdominal tuberculosis in Benin city Nigeria. Sahel Med J. 7. Epub ahead of print 28 February 2005. DOI: https://doi.org/10.4314/smj2.v7i4.12885
Webb E, Kali Vanan N, Biswas R. Empirical treatment of tuberculosis: TB or not TB? BMJ Case Rep; 2018. Epub ahead of print 10 July 2018. DOI: https://doi.org/10.1136/bcr-2018-224166
Kebede W, Abebe G, Gudina EK. Role of empiric treatment in hospitalized patients with Xpert MTB/RIF-negative presumptive pulmonary tuberculosis: A prospective cohort study. Int J Infect Dis. 2020;97:30–7. DOI: https://doi.org/10.1016/j.ijid.2020.06.011
Meregildo-Rodriguez ED, Tafur-Ramirez RC, Espino-Saavedra WG, et al. Abdominal tuberculosis misdiagnosed as acute surgical abdomen and carcinomatosis. F1000Res. 2021;10:355. DOI: https://doi.org/10.12688/f1000research.53036.1
Lancella L, Abate L, Cursi L. Abdominal Tuberculosis in Children: A Case Series of Five Patients. Microorganisms; 11. Epub ahead of print 12 March 2023. DOI: https://doi.org/10.3390/microorganisms11030730
Ahmad R, Changeez M, Khan JS. Diagnostic Accuracy of Peritoneal Fluid GeneXpert in the Diagnosis of Intestinal Tuberculosis, Keeping Histopathology as the Gold Standard. Cureus. 2018;10:e3451. DOI: https://doi.org/10.7759/cureus.3451