Weight loss of term babies in 48 hours of life as a tool to predict non-pathological neonatal hyperbilirubinemia

Lalita Wadhwa; Gudipudi Uma Divya Tejaswini; Geshmanjali Kakarala

doi:10.18203/2349-3291.ijcp20251859

Authors

Lalita Wadhwa Department of Paediatrics, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India
Gudipudi Uma Divya Tejaswini Department of Paediatrics, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India
Geshmanjali Kakarala Department of Paediatrics, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20251859

Keywords:

Neonate, Weight, Hyperbilirubinemia, Bilirubin

Abstract

Background: The aim of this study is to analyse the percentage of weight loss in 48 hours in term neonates as a predictor of non-pathological neonatal hyperbilirubinemia.

Methods: The study was carried out in Department of Paediatrics in GITAM Institute of Medical Sciences and Research. A total of 120 babies were studied. Babies with pathological jaundice were excluded from the study.

Results: While 45% of participants in the current study had normal bilirubin levels, 55% had hyperbilirubinemia (TSB>12). Percentage weight loss at 48 hours was positively correlated with total serum bilirubin with correlation coefficient (r) of 0.525 which was statistically significant (p value <0.001). On performing ROC analysis between percentage weight loss at 48 hours and hyperbilirubinemia, it was found that, at an optimum cut off >6.3% weight loss at 48 hours, patient will have hyperbilirubinemia.

Conclusions: According to the above study, there is a clear link between hyperbilirubinemia and weight loss in newborns. Increased levels of bilirubin are strongly correlated with notable weight loss within the first 48 hours of life. Jaundice has been demonstrated to occur if the weight loss is more than 6.3% in the first 48 hours of life.

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