Rosai Dorfman disease: a rare entity
DOI:
https://doi.org/10.18203/2349-3291.ijcp20251880Keywords:
Lymph nodes, Histopathology, Non-Langerhan cells, SteroidsAbstract
Rosai Dorfman disease (RDD), a rare benign proliferative disorder of unknown etiology, stems from abnormal histiocyte accumulation within lymph node sinusoids and extra nodal tissues. While uncommon in paediatric population, RDD clinically simulates lymphoproliferative disorders. This report details a 4-year male patient presenting at a tertiary care centre with progressive bilateral cervical and submandibular lymphadenopathy lacking febrile symptoms. Diagnostic confirmation was achieved through excisional biopsy. RDD is an exclusion-based diagnosis which requires multidisciplinary collaboration and heightened clinical suspicion remains essential for paediatricians and oncologists to facilitate timely intervention and management of this rare entity.
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