DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20170686

Role of probiotics in preterm infants: a randomized controlled trial

Sukanyaa S., Vinoth S., Ramesh S.

Abstract


Background: Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Probiotics are proposed to aid in the quicker colonisation of the preterm gut by various mechanisms thereby providing innumerable health benefits to the preterm infants. Hence we conducted a study to analyse the role of probiotics in preterm babies. Our primary aim was to compare the weight gain pattern among preterm infants: those receiving probiotic and those who did not receive the probiotic.

Methods: Preterm/VLBW babies were selected, randomized and placed into two groups. One group was given the chosen probiotic and the other was kept as control. The weight gain pattern and the duration of hospital stay among the two groups was compared at the end of one month of age.

Results: The average weight gain in the probiotic group was higher than the control group which was statistically significant. (mean difference: 0.230 + 0.11 95% CI: -0.796 to -0.251 p value <0.000).

Conclusions: Our study was yet another evidence proving the utility of probiotics in the field of neonatalogy.

Keywords


Probiotics, Preterm, VLBW

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References


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