The world faces a new viral threat: monkeypox

Authors

  • Archana Reddy Bongurala Department of Pediatrics, Omni Family Health, Bakersfield, CA, USA
  • Sandhya J. Kadam Family HealthCare Network, Visalia, California, USA
  • Vy Nguyen Western University of Health Sciences, California, USA
  • Mira Patel Western University of Health Sciences, California, USA
  • Rishika Sharma Family HealthCare Network, Visalia, California, USA
  • Anshuman Srivastava Family HealthCare Network, Visalia, California, USA

DOI:

https://doi.org/10.18203/2349-3291.ijcp20250352

Keywords:

Monkeypox, Zoonotic disease, Global outbreak, Public health, Prevention

Abstract

Monkeypox, a zoonotic viral disease, has re-emerged globally, presenting a significant public health challenge. Initially affecting primarily men who have sex with men, the virus has demonstrated broader transmission patterns, raising concerns about its potential to become endemic. The recent outbreak has highlighted the rapid spread of Monkeypox through close contact, particularly during sexual activity. This shift in transmission dynamics necessitates a robust global response, including surveillance systems, contact tracing, and vaccination campaigns. Understanding the virus's epidemiology, clinical manifestations, and transmission routes is crucial for effective prevention and control. While supportive care remains the primary treatment, antiviral medications and vaccines offer additional tools to mitigate the impact of Monkeypox outbreaks. Continued vigilance and timely interventions are essential to prevent further spread and protect public health.

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References

Alakunle E, Kolawole D, Diaz-Cánova D, Alele F, Adegboye O, Moens U, et al A comprehensive review of monkeypox virus and mpox characteristics. Front Cell Infect Microbiol. 2024;14:1360586. DOI: https://doi.org/10.3389/fcimb.2024.1360586

Huang Y, Mu L, Wang W. Monkeypox: epidemiology, pathogenesis, treatment and prevention. Signal Transduct Target Ther. 2022;7(1):373. DOI: https://doi.org/10.1038/s41392-022-01215-4

Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. The changing epidemiology of human monkeypox-A potential threat? A systematic review. PLoS Negl Trop Dis. 2022;16(2):e0010141. DOI: https://doi.org/10.1371/journal.pntd.0010141

Kwong J, McNabb KC, Voss JG, Bergman A, McGee K, Farley J. Monkeypox Virus Outbreak 2022: Key Epidemiologic, Clinical, Diagnostic, and Prevention Considerations. J Assoc Nurses AIDS Care. 2022;33(6):657-67. DOI: https://doi.org/10.1097/JNC.0000000000000365

Capobianchi MR, Di Caro A, Piubelli C, Mori A, Bisoffi Z, Castilletti C. Monkeypox 2022 outbreak in non-endemic countries: Open questions relevant for public health, nonpharmacological intervention and literature review. Front Cell Infect Microbiol. 2022;12:1005955. DOI: https://doi.org/10.3389/fcimb.2022.1005955

Parker S, Buller RM. A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012. Future Virol. 2013;8(2):129-57. DOI: https://doi.org/10.2217/fvl.12.130

Gessain A, Nakoune E, Yazdanpanah Y. Monkeypox. N Engl J Med. 2022;387(19):1783-93. DOI: https://doi.org/10.1056/NEJMra2208860

Onchonga D. Monkeypox viral disease outbreak in non-endemic countries in 2022: What clinicians and healthcare professionals need to know. Saudi Pharm J. 2022;30(11):1679-81. DOI: https://doi.org/10.1016/j.jsps.2022.09.008

Hatmal MM, Al-Hatamleh MAI, Olaimat AN, Ahmad S, Hasan H, Ahmad Suhaimi NA, et al Comprehensive literature review of monkeypox. Emerg Microbes Infect. 2022;11(1):2600-31. DOI: https://doi.org/10.1080/22221751.2022.2132882

Falendysz EA, Lopera JG, Rocke TE, Osorio JE. Monkeypox Virus in Animals: Current Knowledge of Viral Transmission and Pathogenesis in Wild Animal Reservoirs and Captive Animal Models. Viruses. 2023;15(4):905. DOI: https://doi.org/10.3390/v15040905

Kantele A, Chickering K, Vapalahti O, Rimoin AW. Emerging diseases-the monkeypox epidemic in the Democratic Republic of the Congo. Clin Microbiol Infect. 2016;22(8):658-9. DOI: https://doi.org/10.1016/j.cmi.2016.07.004

Zahmatyar M, Fazlollahi A, Motamedi A, Zolfi M, Seyedi F, Nejadghaderi SA, et al monkeypox: history, presentations, transmission, epidemiology, diagnosis, treatment, and prevention. Front Med (Lausanne). 2023;10:1157670. DOI: https://doi.org/10.3389/fmed.2023.1157670

Ahmad FB, Cisewski JA, Anderson RN. Mortality in the United States-Provisional Data, 2023. MMWR Morb Mortal Wkly Rep. 2024;73:677-81. DOI: https://doi.org/10.15585/mmwr.mm7331a1

Weekly cases* of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents week ending April 13, 2024 (Week 15). Cdc.gov. Available at: https://wonder.cdc.gov/nndss/static/ 2024/15/2024-15-table968.html. Accessed on 24 November 2024.

CDC. Mpox in the United States and around the world: Current situation. Mpox. Available at: https://www.cdc.gov/mpox/situation-summary/ index.html. Accessed on 24 November 2024.

McCollum AM, Damon IK. Human monkeypox. Clin Infect Dis. 2014;58(2):260-7. DOI: https://doi.org/10.1093/cid/cit703

Hirani R, Noruzi K, Iqbal A, Hussaini AS, Khan RA, Harutyunyan A, et al. A Review of the Past, Present, and Future of the Monkeypox Virus: Challenges, Opportunities, and Lessons from COVID-19 for Global Health Security. Microorganisms. 2023;11(11):2713. DOI: https://doi.org/10.3390/microorganisms11112713

Weaver JR, Isaacs SN. Monkeypox virus and insights into its immunomodulatory proteins. Immunol Rev. 2008;225:96-113. DOI: https://doi.org/10.1111/j.1600-065X.2008.00691.x

Aden TA, Blevins P, York SW, Rager S, Balachandran D, Hutson CL, et al. Rapid Diagnostic Testing for Response to the Monkeypox Outbreak-Laboratory Response Network, United States, 2022. MMWR Morb Mortal Wkly Rep. 2022;71(28):904-7. DOI: https://doi.org/10.15585/mmwr.mm7128e1

Rizk JG, Lippi G, Henry BM, Forthal DN, Rizk Y. Prevention and Treatment of Monkeypox. Drugs. 2022;82(9):957-63. DOI: https://doi.org/10.1007/s40265-022-01742-y

Lulli LG, Baldassarre A, Mucci N, Arcangeli G. Prevention, Risk Exposure, and Knowledge of Monkeypox in Occupational Settings: A Scoping Review. Trop Med Infect Dis. 2022;7(10):276. DOI: https://doi.org/10.3390/tropicalmed7100276

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Published

2025-02-10

How to Cite

Bongurala, A. R., Kadam, S. J., Nguyen, V., Patel, M., Sharma, R., & Srivastava, A. (2025). The world faces a new viral threat: monkeypox. International Journal of Contemporary Pediatrics, 12(3), 520–523. https://doi.org/10.18203/2349-3291.ijcp20250352

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Section

Review Articles