The world faces a new viral threat: monkeypox
DOI:
https://doi.org/10.18203/2349-3291.ijcp20250352Keywords:
Monkeypox, Zoonotic disease, Global outbreak, Public health, PreventionAbstract
Monkeypox, a zoonotic viral disease, has re-emerged globally, presenting a significant public health challenge. Initially affecting primarily men who have sex with men, the virus has demonstrated broader transmission patterns, raising concerns about its potential to become endemic. The recent outbreak has highlighted the rapid spread of Monkeypox through close contact, particularly during sexual activity. This shift in transmission dynamics necessitates a robust global response, including surveillance systems, contact tracing, and vaccination campaigns. Understanding the virus's epidemiology, clinical manifestations, and transmission routes is crucial for effective prevention and control. While supportive care remains the primary treatment, antiviral medications and vaccines offer additional tools to mitigate the impact of Monkeypox outbreaks. Continued vigilance and timely interventions are essential to prevent further spread and protect public health.
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References
Alakunle E, Kolawole D, Diaz-Cánova D, Alele F, Adegboye O, Moens U, et al A comprehensive review of monkeypox virus and mpox characteristics. Front Cell Infect Microbiol. 2024;14:1360586. DOI: https://doi.org/10.3389/fcimb.2024.1360586
Huang Y, Mu L, Wang W. Monkeypox: epidemiology, pathogenesis, treatment and prevention. Signal Transduct Target Ther. 2022;7(1):373. DOI: https://doi.org/10.1038/s41392-022-01215-4
Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. The changing epidemiology of human monkeypox-A potential threat? A systematic review. PLoS Negl Trop Dis. 2022;16(2):e0010141. DOI: https://doi.org/10.1371/journal.pntd.0010141
Kwong J, McNabb KC, Voss JG, Bergman A, McGee K, Farley J. Monkeypox Virus Outbreak 2022: Key Epidemiologic, Clinical, Diagnostic, and Prevention Considerations. J Assoc Nurses AIDS Care. 2022;33(6):657-67. DOI: https://doi.org/10.1097/JNC.0000000000000365
Capobianchi MR, Di Caro A, Piubelli C, Mori A, Bisoffi Z, Castilletti C. Monkeypox 2022 outbreak in non-endemic countries: Open questions relevant for public health, nonpharmacological intervention and literature review. Front Cell Infect Microbiol. 2022;12:1005955. DOI: https://doi.org/10.3389/fcimb.2022.1005955
Parker S, Buller RM. A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012. Future Virol. 2013;8(2):129-57. DOI: https://doi.org/10.2217/fvl.12.130
Gessain A, Nakoune E, Yazdanpanah Y. Monkeypox. N Engl J Med. 2022;387(19):1783-93. DOI: https://doi.org/10.1056/NEJMra2208860
Onchonga D. Monkeypox viral disease outbreak in non-endemic countries in 2022: What clinicians and healthcare professionals need to know. Saudi Pharm J. 2022;30(11):1679-81. DOI: https://doi.org/10.1016/j.jsps.2022.09.008
Hatmal MM, Al-Hatamleh MAI, Olaimat AN, Ahmad S, Hasan H, Ahmad Suhaimi NA, et al Comprehensive literature review of monkeypox. Emerg Microbes Infect. 2022;11(1):2600-31. DOI: https://doi.org/10.1080/22221751.2022.2132882
Falendysz EA, Lopera JG, Rocke TE, Osorio JE. Monkeypox Virus in Animals: Current Knowledge of Viral Transmission and Pathogenesis in Wild Animal Reservoirs and Captive Animal Models. Viruses. 2023;15(4):905. DOI: https://doi.org/10.3390/v15040905
Kantele A, Chickering K, Vapalahti O, Rimoin AW. Emerging diseases-the monkeypox epidemic in the Democratic Republic of the Congo. Clin Microbiol Infect. 2016;22(8):658-9. DOI: https://doi.org/10.1016/j.cmi.2016.07.004
Zahmatyar M, Fazlollahi A, Motamedi A, Zolfi M, Seyedi F, Nejadghaderi SA, et al monkeypox: history, presentations, transmission, epidemiology, diagnosis, treatment, and prevention. Front Med (Lausanne). 2023;10:1157670. DOI: https://doi.org/10.3389/fmed.2023.1157670
Ahmad FB, Cisewski JA, Anderson RN. Mortality in the United States-Provisional Data, 2023. MMWR Morb Mortal Wkly Rep. 2024;73:677-81. DOI: https://doi.org/10.15585/mmwr.mm7331a1
Weekly cases* of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents week ending April 13, 2024 (Week 15). Cdc.gov. Available at: https://wonder.cdc.gov/nndss/static/ 2024/15/2024-15-table968.html. Accessed on 24 November 2024.
CDC. Mpox in the United States and around the world: Current situation. Mpox. Available at: https://www.cdc.gov/mpox/situation-summary/ index.html. Accessed on 24 November 2024.
McCollum AM, Damon IK. Human monkeypox. Clin Infect Dis. 2014;58(2):260-7. DOI: https://doi.org/10.1093/cid/cit703
Hirani R, Noruzi K, Iqbal A, Hussaini AS, Khan RA, Harutyunyan A, et al. A Review of the Past, Present, and Future of the Monkeypox Virus: Challenges, Opportunities, and Lessons from COVID-19 for Global Health Security. Microorganisms. 2023;11(11):2713. DOI: https://doi.org/10.3390/microorganisms11112713
Weaver JR, Isaacs SN. Monkeypox virus and insights into its immunomodulatory proteins. Immunol Rev. 2008;225:96-113. DOI: https://doi.org/10.1111/j.1600-065X.2008.00691.x
Aden TA, Blevins P, York SW, Rager S, Balachandran D, Hutson CL, et al. Rapid Diagnostic Testing for Response to the Monkeypox Outbreak-Laboratory Response Network, United States, 2022. MMWR Morb Mortal Wkly Rep. 2022;71(28):904-7. DOI: https://doi.org/10.15585/mmwr.mm7128e1
Rizk JG, Lippi G, Henry BM, Forthal DN, Rizk Y. Prevention and Treatment of Monkeypox. Drugs. 2022;82(9):957-63. DOI: https://doi.org/10.1007/s40265-022-01742-y
Lulli LG, Baldassarre A, Mucci N, Arcangeli G. Prevention, Risk Exposure, and Knowledge of Monkeypox in Occupational Settings: A Scoping Review. Trop Med Infect Dis. 2022;7(10):276. DOI: https://doi.org/10.3390/tropicalmed7100276