A study on mumps infection in children aged 1-12 years in a tertiary care hospital, South India: a cross-sectional study
DOI:
https://doi.org/10.18203/2349-3291.ijcp20243865Keywords:
Aseptic meningitis, Mumps, National immunization schedule, Parotid swelling, VaccineAbstract
Background: Mumps is a highly contagious disease effecting children globally with disease presentation varying from being asymptomatic to unilateral or bilateral parotid gland enlargement. It causes serious complications like orchitis, aseptic meningitis, pancreatitis etc. During introduction of MR vaccine in NIS by the Government of India, Mumps vaccine was not included due to lack of enough data representing actual burden of the disease in our country.
Methods: This study was done from January 2024 to August 2024 following a surge in Mumps cases in children aged 1 to 12 years attending paediatrics department, Rangaraya Medical College, Kakinada.
Results: A total of 76 children were included in the study. Children were mostly in the age group 6-10 years (44). Both male (37) and female (36) children were equally affected. Most of the children were from rural areas (67%). 75 (98.7%) children were completely vaccinated with the majority being vaccinated in the Government sector (86.85%). Only 9 (11.85%) children received mumps vaccine. Contact with an individual with mumps was seen in 51 children (67.11%). The majority of the cases were reported during the months of March-April (89.47%). All 76 children presented with parotid swelling either unilateral (22) or bilateral (52) with 2 children having both parotid and submandibular gland swellings. Mumps-related complications like pancreatitis, aseptic meningitis and both were seen in 6 cases,4 cases and 2 cases respectively.
Conclusions: The government of India is to take necessary action to include the mumps vaccine in the UIP along with the MR vaccine to prevent mumps and its complications.
Metrics
References
Ashishtha VM, Yadav S, Dabas A. IAP position paper on the burden of mumps in India and vaccination strategies. Indian Pediatr. 2015;52:505-14.
Betáková T, Svetlíková D, Gocník M. Overview of measles and mumps vaccine: Origin, present and future of vaccine production. Acta Virol. 2013;57:91-6.
Rubin S, Kennedy R, Poland G. Emerging mumps infection. Pediatr Infect Dis J. 2016;35:799-801.
Paul S, Mahajan PB, Sahoo J, Bhatia V, Subba SH. Investigating Mumps Outbreak in Odisha, India: An Opportunity to Assess the Health System by Utilizing the Essential Public Health Services Framework. Am J Trop Med Hyg. 2017;96(5):1215-21.
Rana MS, Usman M, Alam MM, Tahir M, Ikram A, Zaidi SSZ, et al. The emergence of mumps after the COVID-19 pandemic in Pakistan: Time to consider MMR vaccination strategies. J Infect. 2023;86(5):133-4.
Bashar MD, Gnanasekaran S. Mumps resurgence in India in the decade 2014-2023: a trend and geospatial analysis. 2024. Available from: https://doi.org. Accessed on 12 August 2024.
World Health Organization. Mumps reported cases and incidence. WHO. Available at: https://immunizationdata.who.int. Accessed on 17 August 2024.
World Health Organization. Global Health Observatory Data Repository. Mumps - Reported cases by country. WHO. Available at: https://apps.who.int/gho/data/view.main. Accessed on 21 August 2024.
India Today. Why India is reporting a mumps infection spike. Available from: https://www.indiatoday.in/india. Accessed on 12 August 2024.
Dharmapalan D, Gavhane J, Patil A, Shahane S, Warad S, Yewale Y, et al. Mumps Epidemic in Navi Mumbai in 2023-24: Lessons for the Health Management System. Indian Pediatr. 2024;24:97.
Bhat UM, Mir NY, Farooq W, Zaman BU, Malik MI. Clinical profile of mumps in children in a tertiary care hospital in Kashmir. Int J Contemp Pediatr. 2023;10:290-4.
Moghe CS, Goel P, Singh J. Mumps outbreak investigation in Jaisalmer, Rajasthan, India, June-September 2016. J Med Virol. 2019;91(3):347-50.
Bakker W, Mathias R. Mumps caused by an inadequately attenuated measles, mumps and rubella vaccine. Can J Infect Dis. 2001;12(3):144-8.
Saffar H, Mousavi S, Saffar H. Seroconversion rates following 2 doses of measles-mumps-rubella vaccination given at the ages 12 and 18 months: data for a possible additional dose at older age. BMC Immunol. 2022;23:2.
Gomber S, Arora SK, Das S, Ramachandran VG. Immune response to second dose of MMR vaccine in Indian children. Indian J Med Res. 2011;134(3):302-6.
Saxena B, Ramachandran VG, Saha R, Shah D. Mumps Antibody Titer in MMR-Vaccinated and Vaccine Naïve Children at a Public Hospital in Delhi. Indian Pediatr. 2021;58(2):137-9.
Arshad AS, Shamila H, Khan I, Syed MA. Patterns of mini-outbreaks of mumps at South Kashmir, Pulwama, India 2007-2011. Nitte University J Health Sci. 2013;3:52-5.
Saha I, Haldar D, Paul B, Shrivastava P, Das D, Pal M, et al. An epidemiological investigation of mumps outbreak in a slum of Kolkata. J Commun Dis. 2012;44:29-36.
Paul S, Mahajan PB, Sahoo J, Bhatia V, Subba SH. Investigating Mumps Outbreak in Odisha, India: An Opportunity to Assess the Health System by Utilizing the Essential Public Health Services Framework. Am J Trop Med Hyg. 2017;96(5):1215-21.
Davison P, Rausch-Phung EA, Morris J. Mumps. In: StatPearls. Treasure Island (FL): StatPearls Publishing. Available at: https://www.ncbi.nlm.nih.gov.