A study of body fat distribution-in childhood obesity and its associated metabolic risk factors

Mir Sumsam Ali Khurram

doi:10.18203/2349-3291.ijcp20243850

Authors

Mir Sumsam Ali Khurram Department of Pediatrics, Deccan College of Medical Sciences, Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20243850

Keywords:

Body mass index, Lipid profile and serum fasting glucose level, Systolic and diastolic blood pressure

Abstract

Background: The Objective of the present study was to find out fat distribution pattern in obese children between 6 to 12 years of age as compared to non-obese children of same age.

Methods: A case control study was done between 1st July 2023 to 1st July 2024 on 138 children between 6 to 12 years of age group in Deccan College of Medical Sciences, Hyderabad, Telangana state. Ultra-sonographic measurement of fat thickness including maximum and minimum preperitoneal fat thickness, maximum and minimum abdominal subcutaneous fat, thickness at triceps and subscapular regions were determined in all participants. Fasting blood glucose was measured using enzymatic assay. Total cholesterol was measured by enzymatic assays.

Results: Total 138 children were enrolled in the study. Out of 138 children included in study, the study population included 69 obese (35 females and 34 males) and 69 non-obese children (33 females and 36 males). When both groups were compared, weight, Body mass Index (BMI) and ultra-sonographic measurement of body fat thickness differed significantly.

Conclusions: Obese children have high serum cholesterol, high serum triglyceride and high serum LDL levels as compared to non-obese children. In obese children, higher the fasting serum insulin level, more is the preperitoneal fat layer 5cm above the umbilicus with p-value of <0.05 which is significant.

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References

Sinha R, Fisch G, Teague B. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Engl J Med. 2002;346(11):802-10.

Popkin B. Global dynamics in childhood obesity: reflections on a life of work in the field. Pedia Obes: Etiol, Pathogen, and Treat. 2010:3-11.

Hayden-Wade HA, Stein RI, Ghaderi A, Saelens BE, Zabinski MF, Wilfley DE. Prevalence, characteristics and correlates of teasing experiences among overweight children vs. non-overweight peers. Obes Res. 2005;13(8):1381-92.

Duren DL, Sherwood RJ, Czerwinski SA, Lee M, Choh AC, Siervogel RM, et al. Body composition methods: comparisons and interpretation. J Diabetes Sci Technol. 2008;2(6):1139-46.

Xu S, Xue Y. Pediatric obesity: Causes, symptoms, prevention and treatment. Exp Ther Med. 2016;11(1):15-20.

Wills M. Orthopedic complications of childhood obesity. Pediatr Phys Ther. 2004;16(4):230-5.

Flynn JT. Pediatric hypertension: recent trends and accomplishments, future challenges. Am J Hypertens. 2008;21(6):605-12.

Semiz S, Ozgoren E, Sabir N, Semiz E. Body fat distribution in childhood obesity: association with metabolic risk factors. Indian Pediatr. 2008;45(6):457-62.

Kanai, H. and Matsuzawa, Yuji and Fujioka, S. and Tokunaga, Kan and Tarui, S.. (1992). A Close Correlation of Fasting Insulin Levels to Blood Pressure in Obese Children. 2007;10:-3512-3.

Nishina M, Kikuchi T, Yamazaki H, Kameda K, Hiura M, Uchiyama M. Relationship among Systolic Blood Pressure, Serum Insulin and Leptin and Visceral Fat Accumulation in Obese Children, Hypertens Res. 2003;26:281-8.

Tershakovec AM, Kuppler KM, Zemel BS. Body composition and metabolic factors in obese children and adolescents. Int J Obes Relat Metab Disord. 2003;27(1):19-24.

Asayama K, Sato A, Ohkubo T. The association between masked hypertension and waist circumference as an obesity-related anthropometric index for metabolic syndrome: the Ohasama study. Hypertens Res. 2009;32,438–43.

Jafar TH. Children, obesity and high blood pressure: Asian populations at high risk. Am J Hypertens. 2009;22(1):6-7.

Steinberger J, Moorehead C, Katch V, Rocchini AP. Relationship between insulin resistance and abnormal lipid profile in obese adolescents. J Pediatr. 1995;126(5):690-5.

Patel A, Barzi F, Jamrozik K. Serum triglycerides as a risk factor for cardiovascular diseases in the Asia-Pacific region. Circulation. 2004;110(17):2678-86.

Pulgarón ER. Childhood obesity: a review of increased risk for physical and psychological comorbidities. Clin Ther. 2013;35(1):18-32.