Comparison of nasal masks or binasal prongs for delivering continuous positive airway pressure in preterm neonates of gestational age less than 32 weeks
DOI:
https://doi.org/10.18203/2349-3291.ijcp20242737Keywords:
Preterm, Respiratory distress, NCPAP, Mechanical ventilator, Nasal mask, Nasal prongsAbstract
Background: Aim was to compare the efficacy and safety of continuous positive airway pressure (CPAP) delivered by nasal masks vs binasal prongs.
Methods: This was observational trial where preterm infants less than 32 weeks of gestation with respiratory distress were enrolled after parental consent. Participants: 145 neonates less than 32 weeks gestation requiring nasal CPAP (NCPAP) as a primary mode for respiratory distress, who were treated with either nasal mask (n=45) or nasal prongs (n=99) as interface. Primary outcome: Was the incidence of CPAP failure (need for mechanical ventilation at less than 72 hours).
Results: Failure rate in nasal mask group was 13% vs nasal prongs group was 39.4% and the difference was statistically significant. Secondary outcomes were mean FiO2 requirement at 6 hours, duration of CPAP therapy, hospital stay and nasal trauma. There was 3.7±5.78% reduction in oxygen requirement at 6 hours of CPAP initiation with nasal mask as compared to nasal prongs and the difference was statistically significant (p<0.05). the CPAP duration in nasal mask group was 3.4± 4.04 days vs nasal prongs group was 4.5±3.52 days and duration of hospital stay in nasal mask group was 15.4±14.19 vs in nasal prongs group was 20.2±13.86 and the both differences were also statistically significant(p<0.05). Nasal mask had no nasal injury (0%) as compared to infants on nasal prongs (23.2%) and the difference was statistically significant (p<0.05).
Conclusions: NCPAP with mask as interface is as effective as prongs but causes less nasal trauma and less CPAP duration and hospital stay.
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References
Yadav S, Lee B, Kamity R. Neonatal respiratory distress syndrome StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.
Kliegman, Stanton. Nelson’s Textbook of Pediatrics 19th Edition, Vol. I, Independently Published. 2012;581-90.
Rodriguez RJ, Martin RJ. Respiratory distress syndrome and its management. Fannorott and Martin (eds). Neonatal and Infants, 7th Edition. St. Louis. 2002;1001-11.
Kleigman, ST Geme, Nelson's textbook of Pediatrics 21st Edition; 2019;1:3998.
Singh M. Hyaline membrane disease care of new born. 6th Edition. 2004;268-70.
Kumar P, Sandesu Kiran PS. Changing trend in the management of RDS. Indian J Pediatr. 2004;7(11):49-54.
Child health program. Available at: https://main. mohfw.gov.in. Accessed on 20 November 2022.
Support Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network, Finer NN, Carlo WA, Walsh MC, Rich W, Gantz MG, et al. Early CPAP versus surfactant in extremely preterm infants. N Engl J Med. 2010;362:1970.
Balard JL, Knoury JC, Wedig K, Wang L, Eilers-Walsman BL, Lipp R, et al. New Ballard score, expanded to include extremely premature infants. J Pediatri. 1991;119(3):417-23.
Kiran S, Murki S, Pratap OT, Kandraju H, Reddy A. Nasal continuous positive airway pressure therapy in a nontertiary neonatal unit: Reduced need for up-transfers. Indian J Pediatr. 2014;82(2):126-30.
Chandrasekaran A, Sachdeva A, Sankar MJ, Agarwal R, Deorari AK, Paul VK. Nasal mask versus nasal prongs in the delivery of continuous positive airway pressure in preterm infants-An open label randomized controlled trial. E-PAS. 2014;2936:512.
Urs PS, Khan F, Maiya PP. Bubble CPAP-a primary respiratory support for respiratory distress syndrome in newborns. Indian Pediatr. 2009;46(5):409-11.
Koti J, Murki S, Gaddam P, Reddy A, Reddy MD. Bubble CPAP for respiratory distress syndrome in preterm infants. Indian Pediatr. 2010;47(2):139-43.
Yong SC, Chen SJ, Boo NY. Incidence of nasal trauma associated with nasal prong versus nasal mask during continuous positive airway pressure treatment in very low birthweight infants: a randomised control study. Arch Dis Child Fetal Neonatal Ed. 2005;90(6):480-3.