A case report on Kawasaki disease
DOI:
https://doi.org/10.18203/2349-3291.ijcp20242025Keywords:
IVIG, Strawberry tongue, Consanguineous marriageAbstract
Kawasaki disease (KD) is a significant pediatric condition characterized by diverse clinical manifestations and potential cardiovascular complications. This case report examines a 4-year- old male child, third in birth order from a consanguineous marriage, presenting with a 14-day history of fever, strawberry tongue, peri-oral and peri-anal excoriation, and skin peeling on the upper limbs. Clinical examination revealed bilateral bulbar conjunctival injection and cervical lymphadenopathy. Laboratory findings indicated systemic inflammation, supporting the KD diagnosis according to established criteria. The child was treated with intravenous fluids (IVF), paracetamol, intravenous immunoglobulin (IVIG), aspirin, and topical calamine lotion. The treatment regimen led to favorable patient outcomes, although the consanguineous background suggests potential genetic predisposition. This case underscores the critical need for timely diagnosis and intervention in KD to prevent severe cardiac complications. It highlights the importance of adhering to diagnostic criteria and prompt therapeutic measures, contributing to improved understanding and management of KD in pediatric practice. Further research is recommended to explore genetic factors influencing KD.
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Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: A statement for health professionals from the Committee of Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. 2004;114(6):1708-33.
Singh S, Vignesh P, Burgner D. The epidemiology of Kawasaki disease: a global update. Arch Dis Child. 2015;100(11):1084-8.
Suddleson EA, Reid B, Woolley MM, Takahashi M. Hydrops of the gallbladder associated with Kawasaki syndrome. J Pediatr Surg. 1987;22(10):956-9.
Durongpisitkul K, Gururaj VJ, Park JM, Martin CF. The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics. 1995;96(6):1057-61.
Furusho K, Kamiya T, Nakano H, Kiyosawa N, Shinomiya K, Hayashidera T, et al. High-dose intravenous gamma globulin for Kawasaki disease. Lancet. 1984;2(8411):1055-8.
Newburger JW, Takahashi M, Burns JC, Beiser AS, Chung KJ, Duffy CE, et al. The treatment of Kawasaki syndrome with intravenous gamma globulin. N Engl J Med. 1986;315(6):341-7.
Morikawa Y, Ohashi Y, Harada K, Asai T, Okawa S, Nagashima M, et al. A multicenter, randomized, controlled trial of intravenous gamma globulin therapy in children with acute Kawasaki disease. Acta Paediatr Jpn. 1994;36(4):347-54.
Terai M, Shulman ST. Prevalence of coronary artery abnormalities in Kawasaki disease is highly dependent on gamma globulin dose but independent of salicylate dose. J Pediatr. 1997;131(6):888-93.
Lee HK, Kim DS, Noh GW, Lee KY. Effects of intravenous immune globulin on the peripheral lymphocyte phenotypes in Kawasaki disease. Yonsei Med J. 1996;37(5):357-63.
McCrindle BW, Rowley AH, Newburger JW, Jane CB, Anne FB, Michael G, et al. Diagnosis, Treatment, and Long- Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals from the American Heart Association. Circulation. 2017;135(17):e927-99.
Singh S, Agarwal S, Bhattad S. Kawasaki disease: Etiopathogenesis and novel treatment strategies. Indian Pediatr. 2018;55(7):577-86.
Nakamura Y, Yashiro M, Uehara R, Atsuko S, Satoshi T, Yasuko A, et al. Epidemiologic features of Kawasaki disease in Japan: Results of the 2009-2010 nationwide survey. J Epidemiol. 2012;22(3):216-21.
Newburger JW, Takahashi M, Gerber MA, Michael HG, Lloyd YT, Jane CB, et al. Diagnosis, Treatment, and Long- Term Management of Kawasaki Disease. Circulation. 2016;134(17):2747-71.
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