Recurrent hydrocephalus with neural tube defect: a case report

Authors

  • Setu Rathod Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College & Research Institute, Pillaiyarkuppam, Puducherry, India
  • Sunil Kumar Samal Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College & Research Institute, Pillaiyarkuppam, Puducherry, India
  • Akshay Kumar Mohapatro Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College & Research Institute, Pillaiyarkuppam, Puducherry, India
  • Jasmina Begum Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College & Research Institute, Pillaiyarkuppam, Puducherry, India
  • Seetesh Ghose Department of Obstetrics & Gynecology, Mahatma Gandhi Medical College & Research Institute, Pillaiyarkuppam, Puducherry, India

Keywords:

Recurrent congenital hydrocephalus, Neural tube defect, Periconceptional folic acid

Abstract

The occurrence of congenital hydrocephalus in successive pregnancies is a rare event. Several modes of genetic transmission have been suggested for familial cases of hydrocephalus. The most common heritable pattern of inheritance is X-linked recessive aqueductal stenosis which carries 25% risk of recurrence in future pregnancies with 50% risk for male fetuses. In families where multiple siblings of both the sexes are affected, an autosomal recessive inheritance due to consanguinity has been an alternative explanation. We report a case of female baby with congenital hydrocephalus and lumbar myelomeningocele who was born of a mother with a history of male babies with congenital hydrocephalus in her previous two pregnancies. She had first degree consanguinity with her husband. We discuss the possible differential diagnoses and etiological factors.

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Published

2017-02-07

How to Cite

Rathod, S., Samal, S. K., Mohapatro, A. K., Begum, J., & Ghose, S. (2017). Recurrent hydrocephalus with neural tube defect: a case report. International Journal of Contemporary Pediatrics, 1(3), 172–174. Retrieved from https://www.ijpediatrics.com/index.php/ijcp/article/view/606