Embryonal rhabdomyosarcoma of hard palate: a case report and review of literature

Authors

  • Atreya Guruprasad Department of Pediatrics, Sri. Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India
  • Rachana Insol Visagan Department of Pediatrics, Sri. Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India
  • Latha M. S. Department of Pediatric Hematology and Oncology, Sri. Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India
  • Anantanarayanan P. Department of Oral and Maxillofacial Surgery, Meenakashiammal Dental College, Chennai, Tamil Nadu, India
  • Kavitha Bottu Department of Oral Pathology and Microbiology, Meenakashiammal Dental College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20241046

Keywords:

Child, Oral cavity, Polypoid swelling, RMS

Abstract

Rhabdomyosarcomas are the most common malignant soft tissue tumors in children and adolescents. Around 40% of cases are diagnosed in head and neck region with orbit and face being the commonly involved areas. Oral lesions account for less than 10%. We report a case of embryonal RMS in a 4-year-old boy who presented with a polypoid mass in the hard palate. Though majority of the oral lesions encountered in children are benign, a small but significant percentage may be representative of an aggressive malignant tumor. Differentiating benign and malignant oral lesions is mandatory for optimal diagnostic strategies.

References

Wang C. Childhood rhabdomyosarcoma: recent advances and prospective views. J Dent Res 2012; 91:341-50.

Gillespie MB, Marshall DT, Day TA, Mitchell AO, White DR, Barredo JC. Pediatric rhabdomyo-sarcoma of the head and neck. Curr Treat Options Oncol. 2006;7:13 22.

Hicks J, Flaitz C. Rhabdomyosarcoma of the head and neck in children. Oral Oncol. 2002;38:450-9.

Singh GB, Arora R, Kumar D, Jain M, Puri V. A rare case of congenital rhabdomyosarcoma with review of the literature. Case Rep Otolaryngol. 2013;2013:518.

Mohan KK, Lal A. Congenital embryonal rhabdomyosarcoma of the tongue. Anesth Analg. 1992;74:930 1.

Meehan S, Davis V, Brahim JS. Embryonal rhabdomyosarcoma of the floor of the mouth. A case report. Oral Surg Oral Med Oral Pathol. 1994; 78:603 6.

Hughes A L, Yang E, Vargas S O. A pediatric soft palate mass. JAMA Otolaryngol Head Neck Surg. 2015;141:391-2.

Wachtel M, Dettling M, Koscielniak E, Stegmaier S, Treuner J, Simon-Klingenstein K, et al. Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t (2; 2)(q35; p23) translocation fusing PAX3 to NCOA1. Cancer Res. 2004;64:5539-45.

Manor E, Joshua BZ, Nash M, Brennan PA, Bodner L. Cytogenetics of primary embryonal rhabdomyosarcoma of the cheek. Br J Oral Maxillofac Surg. 2012;50:788-90.

Pontes F, de Oliveira J, de Souza L, Almeida OP, Fregnani ER, Vilela RS, et al. Clinicopathological analysis of head and neck rhabdomyosarcoma: a series of 10 cases and literature review. Med Oral Patol Oral Cir Bucal. 2018;23:e188-97.

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Published

2024-04-25

Issue

Section

Case Reports