ABO/Rh incompatibility in neonatal jaundice: a tertiary hospital based cross sectional study
DOI:
https://doi.org/10.18203/2349-3291.ijcp20231490Keywords:
Neonatal jaundice, ABO incompatibilityAbstract
Background: Neonatal hyperbilirubinemia, defined as a total serum bilirubin level above 5 mg/dl (86 μmol/l). Haemolytic disease of the newborn due to blood group incompatibilities between mother and foetus is one of the commonest cause of hyperbilirubinemia in the newborn.
Methods: A Hospital based cross sectional study was conducted among newborns admitted with jaundice.
Results: In our study 51 cases of neonatal jaundice were due to ABO incompatibility and among them 24 were having O-A incompatibility and 27 were having O-B incompatibility. The mean serum bilirubin in patients with ABO incompatibility were higher (24.8) than those without ABO incompatibility.
Conclusions: In the present study, one third of newborns with neonatal jaundice were having ABO incompatibility. The mean serum bilirubin in patients with ABO incompatibility were higher than those without ABO incompatibility. This highlights the importance of recognizing ABO Rh incompatibility in neonatal jaundice.
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References
Singh M. Care of the Newborn. 8th ed. New Delhi: CBS Publishers and Distributors Pvt Ltd. 2015.
Park K. Park’s Textbook of Preventive and Social Medicine. 24th ed. Jabalpur: Banarsidas Bhanot Publishers. 2017.
Stark AR, Bhutani VK. Neonatal Hyperbilirubinemia. In: Eichenwald EC, Hansen AR, Martin CR, Stark AR, editors.Cloherty and Starks Manual of Neonatal Care.8th ed. Philadelphia: Lippincott. 2018;335-52.
Kumar A, Kumar Patel M, Chavda B, Ranjan A, Ahmad F. Hemolytic disease of the newborn: A study of 50 cases. IJSS. 2013;1(3):95.
Akgul A, Korkmaz A, Yigit S, Yurdakok M. Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter? Turk J Pediatrica. 2013;55:506-9.
Shah A, Shah CK, Venu S. Study of hematological parameters among neonates admitted with neonatal jaundice. J Evolution Med Dental Sci. 2012;1(3):203-8.
Awasthi S, Rehman H. Early prediction of neonatal hyperbilirubinemia. Indian J Pediatr. 1998;65:131-9.
Kalakheti BK, Singh R, Bharra NK, Baral N. Risk of neonatal hyperbilirubinemia in babies born to ‘O’ positive mothers: a prospective cohort study. Kathmandu Univ Med J. 2009;7(25):11-5.
Ella EE, Garba SA, Ogal WN. ABO Incompatibility and its role in neonatal jaundice in Zaria, Kaduna state of Nigeria. IJES. 2013;2(11):17-23.
Bhat Y, Pavan KC. Morbidity of ABO haemolytic disease in the newborn. Paediatr Int Child Health 2012;32:93-6.