Clinical, laboratory, and etiological profile of three infants with neonatal cholestasis and review of literature
DOI:
https://doi.org/10.18203/2349-3291.ijcp20231503Keywords:
Cholestasis, Biliary atresia, Infections, Toxoplasmosis, CytomegalovirusAbstract
Neonatal cholestasis occurs due to failure of the excretion of bile. This happens due to defects in intrahepatic bile production, defects in transmembrane transport of bile, or mechanical obstruction to the flow of bile. Etiology varies from biliary atresia, choledochal cyst, inborn errors of metabolism, neonatal hepatitis, progressive familial intrahepatic cholestasis, congenital infections, etc. Our 3 patients presented with hepatomegaly, splenomegaly, pale stools, and dark urine. We hereby report all these Indian infants presented with cholestasis and discussed in detail regarding clinical, laboratory, and etiological profiles of all.
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