Clinical correlates, characteristics and comorbidities of paediatric tic disorders
DOI:
https://doi.org/10.18203/2349-3291.ijcp20232236Keywords:
Tic disorders, Comorbid disorders, ADHD, Motor tics, SLDAbstract
Background: Tic disorders are complex neuropsychiatric disorders of childhood onset. The associated comorbidities in paediatric tic disorders are of vast importance as they account for the major functional impairment in these children, data of which is lacking in our Indian context.
Methods: Descriptive Cross-sectional study conducted among children of 3-15 years of age in child psychiatry department of Institute of Child health, Egmore, Chennai
Results: In this study 60 patients were studied of whom 47 were male and 13 were females. Comorbid psychiatric disorders were present in 38 (63.3%) children. They were ADHD (48.3%), OCD (6.6%), ASD (6.6%), SLD (20%), Behavioural problems in 16.6%. Motor tics were the most common type of tics. Significant correlation between tic severity and presence of comorbid psychiatric disorders was seen.
Conclusions: Tic disorders are not completely benign and simple as it is thought. Tic disorders usually present with associated comorbidities, which cause more impairment than tics themselves. ADHD is the most common comorbidity associated with paediatric tic disorders.
References
Robertson MM. The prevalence and epidemiology of Gilles de la Tourette syndrome: The epidemiological and prevalence studies. J Psychosom Res. 2008;65: 461-72.
Robertson MM. The prevalence and epidemiology of Gilles de la Tourette syndrome: Tentative explanations for differing prevalence figures in GTS, including the possible effects of psychopathology, aetiology, cultural differences, and differing phenotypes. J Psychosom Res. 2008;65:473-86.
Pauls DL, Leckman JF. The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission. N Engl J Med. 1986;315(16):993-7.
Kalanithi PS, Zheng W, Kataoka Y, DiFiglia M, Grantz H, Saper CB, et al. Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome. Proceed Natl Acad Sci. 2005;102:13307-12.
Robertson MM. The prevalence and epidemiology of Gilles de la Tourette syndrome: The epidemiological and prevalence studies. J Psychosom Res. 2008; 65:461-72.
Bloch MH, Peterson BS, Scahill L, Otka J, Katsovich L, Zhang H, et al. Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome. Arch Pediatr Adolesc Med. 2006;160:65-9.
Peterson BS, Leckman JF. The temporal dynamics of tics in Gilles de la Tourette syndrome. Biol Psychiatry. 1998;44:1337-48.
Khalifa N, von Knorring AL. Tourette syndrome and other tic disorders in a total population of children: Clinical assessment and background. Acta Paediatr. 2005;94:1608-14.
Khalifa N, von Knorring AL. Psychopathology in a Swedish population of school children with tic disorders. J Am Acad Child Adolesc Psychiatr. 2006; 45:1346-53.
Walkup JT, Khan S, Schuerholz L, Paik YS, Leckman JF, Schultz RT. Phenomenology and natural history of tic-related ADHD and learning disabilities. In: Leckman JF, Cohen DJ, eds. Tourette’s syndrome tics, obsessions, compulsions developmental psycho-pathology and clinical care. New York: John Wiley and Sons; 1998:63-79.
Lanzi G, Zambrino CA, Termine C, Palestra M, Ferrari-Ginevra O, Orcesi S, et al. Prevalence of tic disorders among primary school students in the city of Pavia, Italy. Arch Dis Child. 2004;89(1):45-7.
Gorman DA, Thompson N, Plessem KJ, Robertson MM, Leckman JF, Peterson BS. A controlled study of psychosocial outcome and psychiatric comorbidity in children with Tourette syndrome followed up in late adolescence. Am J Psychiatr. 2005;12:34-8.
Woods DW, Piacentini J, Himle MB, Chang S. Premonitory Urge for Tics Scale (PUTS): initial psychometric results and examination of the premonitory urge phenomenon in youths with Tic disorders. J Dev Behav Pediatr. 2005;26:397-403.
Francesco C, Angela R, Larissa B, Flavia C. Psychopathological problems in children affected by tic disorders Study on a large Italian population. Eur Child Adolesc Psychiatr. 2004;13:166-71.
Freeman RD. Tic disorders and ADHD: answers from a world-wide clinical dataset on Tourette syndrome Eur Child Adolesc Psychiatr. 2007;16)1):15-23.
Hounie AG, Goodman WK, Storch EA, Geffken GR, Murphy TK. Obsessive-compulsive disorder in Tourette syndrome. J Child Neurol. 2006;21(8):704-14.
Baron-Cohen S, Mortimore C, Moriarty J, Izaguirre J, Robertson M. The prevalence of Gilles de la Tourette's syndrome in children and adolescents with autism. J Child Psychol Psychiatry. 1999;40(2):213-8.
