Risk factors for asphyxia neonatorum in full-term newborns at the University Hospital of Mahajanga Madagascar

Safidisoa N. Razanamanana; Henintsoa N. Raveloharimino; Setra H. Rambeloson; Norotiana H. Rabesandratana; Diavolana K. Andrianarimanana

doi:10.18203/2349-3291.ijcp20231138

Authors

Safidisoa N. Razanamanana Department of Medicine, Mahajanga University, Madagascar https://orcid.org/0000-0002-4724-4032
Henintsoa N. Raveloharimino Department of Medicine, Mahajanga University, Madagascar
Setra H. Rambeloson Department of Medicine, Mahajanga University, Madagascar
Norotiana H. Rabesandratana Department of Medicine, Mahajanga University, Madagascar
Diavolana K. Andrianarimanana Department of Medicine, Mahajanga University, Madagascar

DOI:

https://doi.org/10.18203/2349-3291.ijcp20231138

Keywords:

Asphyxia neonatorum, Risk factors, Full term newborn

Abstract

Background: The aim of this survey was to study the risk factors associated with asphyxia neonatorum in full-term newborns in the neonatal unit in Child and Mother Complex at Androva Mahajanga Hospital.

Methods: This was a retrospective case-control study conducted from August 2016 through September 2018.

Results: The prevalence of neonatal asphyxia was 5.9%. Determinant factors for birth asphyxia were maternal education level below the tenth grade [OR=1.8 (1.2-2.6), p=0.003] especially if the mother was illiterate [OR=2.3 (1.5-3.6), p<0.001]; less than four prenatal care check-ups [OR=2.9 (1.7-4.9), p<0.001]; presence of maternal disease during pregnancy [OR=2.4 (1.6-3.6), p<0.001], arterial hypertension [OR=3.4 (1.6-7.2), p<0.001]; duration of labour ≥24h [OR=2.1 (1.2-3.6); p=0.007] ; rupture of membranes ≥12h [OR=2.9 (1.6-5.3), p<0.001]; labour outside teaching hospital [OR=21,1 (8,9-49,5), p<0,001]; home birth [OR=26.7 (3.6-199), p<0.001].

Conclusions: Good monitoring of pregnancy, training of providers in neonatal resuscitation, and an increase in technical platforms could reduce the incidence of perinatal asphyxia.

Metrics

Metrics Loading ...

References

Ahearne CE, Boylan GB, Murray DM. Short and long term prognosis in perinatal asphyxia: An update. World J Clin Pediatr. 2016;5(1):67-74.

Thiam L, Dramé A, Coly IZ, Diouf FN, Sylla A, Ndiaye O. Asphyxie périnatale au service de néonatalogie de l’Hopital de la paix de Zinguinchor (Senegal). European Scientific Journal. 2017;13:21:1857-7881.

WHO. Guidelines on basic newborn resuscitation [Internet]. WHO; 2012. Available on the URL : https://apps.who/iris/handle/10665/75157.

Antonucci R, Porcella A, Dolores M. Perinatal asphyxia in the term newborn. Journal of Pediatric and Neonatal Individualized Medicine. 2014:3;2.

Kaye D. Antenatal ant intrapartum risk factors for birth asphyxia among emergency obstétricals referrals in Mulago hospital, Kampala, Uganda. East Afr Med J. 2003;80(3):140-3.

Majeed R, Memon Y, Majeed F, Shaikh NP, Rajar UD. Risk factors of birth asphyxia. J Ayub Med coll Abbottabad. 2007;9(3):67-71.

Clark SM, Basraon SK, Hankins GVD. Intrapartum Asphyxia, Neonatal Encephalopathy, Cerebral Palsy, and Obstetric Interventions in the Term and Near-Term Infant. Neoreviews. 2013.

Bouiller P, Dreyfus M, Mortamet G, Guillois B, Benoist G. Asphyxie perpartum à terme : facteurs de risque de survenue et conséquences à court terme: à propos de 82 cas. J Gynécol Obstet Biol Reprod. 2016;45(6):626-32.

Wayenberg JL, Vermeylen D, Damis E. Définition de l'asphyxie à la naissance et incidence des complications neurologiques et systémiques chez le nouveau- né à terme. Arch Pediatr. 1998;5:1065-71.

Ndiaye O, Tidane Cisse C, Diouf S, Cisse Bathily A, Diallo D, Lamine Fall A. Facteurs de risque associés à l’asphyxie du nouveau-né à terme à la maternité de l’Hôpital Aristide le Dantec de Dakar. Med Afr Noir. 2008; 55(10):522-8.

Zupan-Simunek V. Asphyxie perinatale à terme : diagnostic, pronostic et éléments de neuroprotection. Arch Pediatr. 2010;17:578-82.

Ibrahim NA, Muhye A, Abdulie S. Prevalence of Birth Asphyxia and Associated Factors among Neonates Delivered in Dilchora Referral Hospital, in Dire Dawa, Eastern Ethiopia. Clinics Mother Child Health. 2017;14:279.

Almeida M, Lalya F, Bagnan L, Djidita Hagre Y, Adedemy JD, Ayivi B. Asphyxie périnatale du nouveau-né à terme : facteurs de risque et pronostic au Centre National Hospitalier et Universitaire (CNHU–HKM) de Cotonou. J Afr Pediatr Genet Med. 2017;1:10-5.

Lodé N, Chabernaud JL, Chouakri O, Casadevall I, Maury I, Lagrue E, et al. Volume de recrutement, charge de travail et morbidité liés aux asphyxies per-partum à terme pour les services mobiles d’urgence et de réanimation (SMUR) pédiatriques. J Gynecol Obstet Biol Reprod. 2003;32:1S98-1S105.

Chahid N, Kabiri M, Mrabet M, Knouni H, Kharbach A, Ansari A, et al. Retentissement fœtal et néonatal de l’hypertension artérielle gravidique : données marocaines. J Pediatr Pueric. 2014:27:111-6.

OMS. Pregnant women must be able to access the right care at the right time, says WHO 2016. Available on URL: who.int/fr/news/item/07-11-2016-pregnant-women-must-be-able-to-access-the-right-cae-at-the-right-time-says-who. Accessed 30 August 2022.

Rasoanindrina SB, Rakotozanany B, Andriamahefa R, Randriambelomanana JA. Rôle de la consultation prénatale dans la survenue d’une éclampsie à la Maternité de Befelatanana, Antananarivo (Madagascar). Rev Anesth Reanim Med Urg Toxicol. 2017;9(1):6-9.

Wood C, Hounslow D, Benning H. Time: an important variable in normal deliveries. J Obstet Gynecol Br Commonow. 1973:80:295-300.

De Graft-Johnson J, Vesel L, Rosen HE, Rawlins B, Abwao S. Assessment of quality of newborn care immediately after birth in health facilities across six sub-Saharan African countries. BMJ. 2017;7:e014680.

Aslam HM, Saleem S, Afzal R, Iqbal U, Saleem SM, Shaikh MW, et al. Risk factors of birth asphyxia. Ital J Pediatr. 2014;1(1):1-9.

Wiegers TA, Van Der Zee J, Keirse M. Transfer from home to hospital: what is its effect on the experience of childbirth? Birth, 1998;25(1):19-24.

Janssen PA, Lee SK, Ryan EM. Outcomes of planned home births versus planned hospital births after régulation of midwifery in British Columbia. Canadian Med Association J. 2002;166(3):315-23.

Hamadoun S, Seydou D, Haoua DK, Assa SK, Lazare C, Baye D, et al. Intervention communautaire pour réduire au Mali la mortalité néonatale due à l'asphyxie. Santé publique 2010;4:471-9.