Clinical spectrum of infants with thiamine responsive pulmonary arterial hypertension

Authors

  • Tanmayi Uppalapati Department of Pediatrics, Raja Rajeswari Medical College and Hospital, Bengaluru, Karnataka, India
  • Yathirajam S. Krishna Department of Pediatrics, Raja Rajeswari Medical College and Hospital, Bengaluru, Karnataka, India
  • Adarsh Eregowda Department of Pediatrics, Raja Rajeswari Medical College and Hospital, Bengaluru, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20230441

Keywords:

Pulmonary arterial hypertension, Infancy, Thiamine

Abstract

Pulmonary arterial hypertension (PAH) is a progressive disorder caused by hypertension in blood vessels from heart to lungs. Exclusively breastfed infants are at the highest risk due to their high metabolic demand and low thiamine level in mothers. Symptoms are observed to be sometimes precipitated with the presence of co morbidity such as sepsis and lower respiratory tract infections. This study explains 10 cases with varied clinical presentation and response to management of different grades of infantile pulmonary arterial hypertension.

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Published

2023-02-23

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Section

Case Series