Cardiovascular accident unveiling rheumatic heart disease
DOI:
https://doi.org/10.18203/2349-3291.ijcp20223428Keywords:
Autoimmune, Rheumatic heart disease, Valvular lesions, Stagnant blood flow, Thrombus, CardioembolismAbstract
Infection with group A Streptococci causes an autoimmune reaction known as acute rheumatic fever (ARF) which leads to chronic cardiac condition called rheumatic heart disease (RHD). Rheumatic involvement of the cardiac valves is one of the sequelae of ARF. The valvular lesions begin as verrucae along the borders of heart valves and tend to resolve leaving a scar once the inflammation subsides. Cardio embolism is seen as the main pathophysiological mechanism of ischemic stroke in RHD.
Metrics
References
Carapetis JR. Rheumatic Heart Disease in Developing Countries. N Engl J Med. 2007;357:439-41.
Wolf PA, Dawber TR, Thomas HE, Kannel WB. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: The fiamingham Study. Neurology. 1978;28(10):973.
Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis. 2005;5(11):685-94.
Global Burden of Disease project. Institute for Health Metrics and Evaluation website. Available at: http://www.healthdata.org/gbd. Accessed on 18 August 2021.
Chockalingam A, Gnanavelu G, Elangovan S, Chockalingam V. Clinical spectrum of chronic rheumatic heart disease in India. J Heart Valve Dis. 2003;12(5):577-81.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation. 2009;119(11):1541-51.