Impact of obesity and allergic rhinitis on childhood asthma

Authors

  • Adarsh E. Department of Pediatrics, Rajarajeswari Medical College and Hospital, Bangalore, Karnataka, India
  • Rajanish K. V. Department of Pediatrics, Rajarajeswari Medical College and Hospital, Bangalore, Karnataka, India
  • Varun Prasannaa P. Department of Pediatrics, Rajarajeswari Medical College and Hospital, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20221371

Keywords:

Asthma, GINA, Asthma control, Obesity, Allergic rhinitis

Abstract

Background: Bronchial asthma has varied presentations in children and its global prevalence is increasing in children. Asthma is associated with various risk factors and comorbidities. The objective of the study was to assess the severity, level of control of asthma in children without comorbidities, with obesity and allergic rhinitis.

Methods: An observational study was conducted in 150 children aged 5-15 years diagnosed to have asthma as per GINA (Global initiative for asthma) guidelines 2019, who are being followed up in the department of pediatrics in asthma clinic in RRMCH. Parents were interviewed and the following data collected like demography, allergy history, treatment history, comorbidities, family history of atopy. Detailed clinical examination was performed including anthropometry-weight, height and BMI recording. Pulmonary function tests was done in all children.

Results: Out of 110 children without comorbidities, 108 (98.2%) had well controlled, 2 (1.8%) had partly controlled, 0 had uncontrolled. Out of 19 children with obesity, 5 (26.3%) had well controlled, 9 (47.4%) had partly controlled, 5 (26.3%) had uncontrolled. Out of 15 children with allergic rhinitis, 6 (40%) had well controlled, 8 (53.3%) had partly controlled, 1 (6.7%) had uncontrolled. With a p value of 0.001, it is statistically significant.

Conclusions: Our study shows severity of asthma increases in children having comorbidities like obesity and allergic rhinitis when compared with children without comorbidities with a significant association. Our study also shows that children having comorbidities like obesity and allergic rhinitis have poor level of asthma control when compared with children without comorbidities with a significant association.

Metrics

Metrics Loading ...

References

International Study of Asthma and Allergies in Childhood (ISAAC). Worldwide variations in the prevalence of bronchial asthma symptoms. Euro Respir J. 2012;12:315-35.

Global initiative for Asthma, GINA asthma guidelines 2019. Available at: https://ginasthma.org/?. Accessed on 20 October 2021.

Mirabelli MC, Hsu J, Gower WA. Comorbidities of asthma in U.S. children. Respir Med. 2016;116:34-40.

Ullmann N, Mirra V, Di Marco A, Pavone M, Porcaro F, Negro V, et al. Asthma: differential diagnosis and comorbidities. Front Pediatr. 2018;6:276.

Masoli M, Fabian D, Holt S, Beasley R; Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy. 2004; 59(5):469-78.

Taylor DR, Bateman ED, Boulet LP. A new perspective on concepts of asthma severity and control. Eur Respir J. 2008;32:545-54.

de Groot EP, Duiverman EJ, Brand PL. Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 2010;36(3):671-8.

Madhur CS, Bhatia SS, Sharma D. Prevalence of asthma in school children of rural areas of Kanpur, Uttar Pradesh. J Evol Mental Dent Sci. 2013;2(29): 5298-5301.

Amir M, Kumar S, Gupta RK. An observational study of bronchial asthma in 6-12 years school going children of Agra district. Indian J Allerg Asthma Immunol. 2015;29(2):62-6.

Kumar P, Singh G, Goyal JP, Khera D, Singh K. Association of common comorbidities with asthma in children: a cross-sectional study. Sudan J Paediatr. 2019;19(2):88-92.

Gallucci M, Carbonara P, Pacilli AMG, di Palmo E, Ricci G, Nava S. Use of symptoms scores, spirometry, and other pulmonary function testing for asthma monitoring. Front Pediatr. 2019;7: 54.

van Aalderen WM, Sprikkelman AB. Inhaled corticosteroids in childhood asthma: the story continues. Eur J Pediatr. 2011;170(6):709-18.

Rachelefsky G. Inhaled corticosteroids and asthma control in children: assessing impairment and risk. Pediatrics. 2009;123(1):353-66.

Jain A, Vinod Bhat H, Acharya D. Prevalence of bronchial asthma in rural Indian children: a cross sectional study from South India. Indian J Pediatr. 2010;77(1):31-5.

Rogliani P, Sforza M, Calzetta L. The impact of comorbidities on severe asthma. Curr Opin Pulm Med. 2020;26(1):47-55.

Nyenhuis SM, Akkoyun E, Liu L, Schatz M, Casale TB. Real-World Assessment of Asthma Control and Severity in Children, Adolescents, and Adults with Asthma: Relationships to Care Settings and Comorbidities. J Allergy Clin Immunol Pract. 2020; 8(3):989-96.e1.

Di Genova L, Penta L, Biscarini A, Di Cara G, Esposito S. Children with Obesity and Asthma: Which Are the Best Options for Their Management? Nutrients. 2018;10(11):1634.

Tosca MA, Del Barba P, Licari A, Ciprandi G. Asthma and rhinitis control study group. the measurement of asthma and allergic rhinitis control in children and adolescents. Children. 2020;7(5):43.

Downloads

Published

2022-05-25

How to Cite

E., A., K. V., R., & P., V. P. (2022). Impact of obesity and allergic rhinitis on childhood asthma. International Journal of Contemporary Pediatrics, 9(6), 542–546. https://doi.org/10.18203/2349-3291.ijcp20221371

Issue

Section

Original Research Articles