A rare case of early onset childhood schizophrenia with predominant negative symptoms
DOI:
https://doi.org/10.18203/2349-3291.ijcp20221082Keywords:
Early onset childhood Schizophrenia, Cognitive impairments, Developmental regression, Pervasive developmental disorders, PsychosisAbstract
Early onset childhood schizophrenia (<13 years) is often a rare disorder with an estimated prevalence of 1 in 30,000 children. The disease is characterized by hallucinations, delusions and cognitive impairments. It tends to present insidiously with a premorbid period of developmental delay or regression with declining academics. Often, the diagnosis of early onset schizophrenia is missed or sometimes misdiagnosed as pervasive developmental disorders. We here present a rare case of 10-year-old boy who showed behavioural abnormalities suggestive of psychosis.
References
Röpcke B, Eggers C. Early-onset schizophrenia: a 15-year follow-up. Eur Child Adolesc Psychiatry. 2005;14:341-50.
Bailly D, De Chouly, De Lenclave MB. Aware and not very studied disorder: childhood-onsetschizophrenia. Acase report. L'encephale. 2004;30(6):540-7.
Hendren RL, Hodde-Vargas J, Yeo RA. Neuro-psycho-physiological study of children at risk for schizophrenia: a preliminary report. J Am Academy of Child and Adolescent Psychiatry. 1995;34(10):1284-91.
Asarnow JR, Tompson MC, McGrath EP. Annotation: childhood-onset schizophrenia: clinical and treatment issues. J Child Psychol Psychiatry Allied Disciplines. 2004;45(2):180-94.
Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC et al. Structural abnormalities in the frontal system in schizophrenia: a magnetic resonance imaging study. Arch General psychiatry. 1986;43:136-44.
Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in schizophrenia. Lancet. 1976;ii:924-6.
Masi G, Mucci M, Pari C. Children with schizophrenia: clinical picture and pharmacological treatment. CNS Drugs. 2006;20(10):841-66.
Weinberger DR. Future of Days Past: Neurodevelopment and Schizophrenia. Schizophr Bull. 2017;43:1164-8.
Rapoport JL, Addington AM, Frangou S, Psych MR. The neurodevelopmental model of schizophrenia: update 2005. Mol Psychiatry. 2005;10(5):434-49.
Kinros J, Reichenberg A, Frangou S. The neurodevelopmental theory of schizophrenia: evidence from studies of early onset cases. Israel J Psychiatry Related Sci. 2010;47(2):110-7.
