Published: 2022-03-24

Congenital macroglossia: case report of a rare disease

Sandesh Srivastava, Rahul Kumar, Money Sachdeva, Richa Raj, Om P. Singh


Macroglossia is a clinical disorder in which the tongue is larger than normal. Enlargement can be true as seen in vascular malformations or it could be due to muscular enlargement The prevalence of congenital macroglossia is less than 5 per 100,000 birth. Various causes include acromegaly, Beckwith-Wiedemann syndrome, congenital hypothyroidism, Down syndrome, and lymphangioma or haemangioma. It may cause significant symptoms in children such as sleep apnea, respiratory distress, drooling of saliva, difficulty in swallowing and dysarthria. Long-standing macroglossia leads to an anterior open bite deformity, increased incidence of upper respiratory tract infections and failure to thrive.


Macroglossia, Tongue reduction, Partial glossectomy

Full Text:



Nunez-Martinez PM, Garcia-Delgado C, Moran-Barroso VF, Jasso-Gutierrez L. Congenital macroglossia: clinical features and therapeutic strategies in paediatric patients. Bol Med Hosp Infant Mex. 2016;73(3):212-6.

Topouzelis N, Iliopoulos C, Kolokitha OE. Macroglossia. Int Dent J. 2011;61(2):63-9.

Prada CE, Zarate YA, Hopkin RJ. Genetic causes of macroglossia: diagnostic approach. Pediatrics. 2012;129(2):431-7.

Kagan KO, Berg C, Dufke A, Geipel A, Hoopmann M, Abele H. Novel fetal and maternal sonographic findings in confirmed cases of Beckwith-Wiedemann syndrome. Prenat Diagn. 2015;35(4):394-9.

Dudhia SB, Dudhia BB. Undetected hypothyroidism: a rare dental diagnosis. J Oral Maxillofac Pathol. 2014;18(2):315-9.

Heggie AA, Vujcich NJ, Portnof JE, Morgan AT. Tongue reduction for macroglossia in Beckwith Wiedemann syndrome: review and application of new technique. Int J Oral Maxillofac Surg. 2013;42(2):185-91.