Clinical and bacteriological profile of urinary tract infection in children at a tertiary care hospital

Bikash Chandra Nag; M. Mizanur Rahman; Mehdi Pervez; Ashis Kumar Halder; M. Mujibur Rahman; Ruksana Begum

doi:10.18203/2349-3291.ijcp20214785

Authors

Bikash Chandra Nag Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh
M. Mizanur Rahman Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh
Mehdi Pervez Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh
Ashis Kumar Halder Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh
M. Mujibur Rahman Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh
Ruksana Begum Department of Pediatrics, Popular College Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2349-3291.ijcp20214785

Keywords:

UTI, Bacterial isolates, Antibiotic susceptibility

Abstract

Background: Urinary tract infection (UTI) is common in children and is an important cause of morbidity. UTI at young age can lead to renal injury and scarring, and ultimately lead to end stage renal disease in adulthood. Aim of the study The objectives of this study were to study the clinical and bacteriological profile of UTI in children.

Methods: This prospective study was done in Sher-E-Bangla medical college hospital, Barishal from January 2018 to July 2019. A urine sample was included in our dataset if it demonstrated pure growth of a single organism and accompanying antimicrobial susceptibility and subject demographic data were available.

Result: UTI was more common in female (70.0%) than in male (33.0%). Half were in the age group 1-5 years. Fever was the most common presentation (64.0%) followed by abdominal pain (42.0%), dysuria /increased frequency (34%), decreased appetite (28%). Escherichia coli was the most common (64%) bacterial isolate followed by Klebsiella sp. (20.0%) and Proteus sp. (14.0%). E. coli was highly sensitive to ofloxacin, cefotaxime and amikacin (94.0%). Klebsiella was 100% sensitive to ciprofloxacin and amikacin. Greater degree of resistance was seen to ampicillin, cotrimoxazole and nalidixic acid.

Conclusions: Though various microorganisms are responsible for UTI in children, E. coli is the most common causative agent. Antimicrobial resistance has already emerged against many antibiotics, making empiric treatment of these infections challenging.

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Author Biography

Bikash Chandra Nag, Department of Pediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh

Assistant Professor, Department of Paediatrics, Sher-E-Bangla Medical College, Barishal, Bangladesh.

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