Atypical hand foot mouth disease presenting as vesiculobullous lesion

Authors

  • Nihil E. Lohidakshan Department of Paediatrics, Masonic Medical Centre for Children, Coimbatore, Tamil Nadu, India
  • Chakravarthi R. Srinivas Department of Dermatology, KIMS, Bhubaneswar, Odisha, India
  • Sruthi Alanghat Department of Paediatrics, Masonic Medical Centre for Children, Coimbatore, Tamil Nadu, India http://orcid.org/0000-0002-0991-2407

DOI:

https://doi.org/10.18203/2349-3291.ijcp20214545

Keywords:

HFMD, Lesion, Papular skin lesions

Abstract

Hand, food, and mouth disease (HFMD) is a highly contagious disease caused by enteroviruses affecting young children under 5 years. Among enteroviruses (EVs), the main pathogens of HFMD are coxsackievirus A16 (CV-A16) and EV-A71 (EV-71).1 The clinical features include a prodromal phase which has low-grade fever, malaise and sore throat. This initial phase is usually followed by enanthem and erythematous papular skin lesions, predominantly affecting palms and soles. The dorsal surface of hands, feet, and perioral skin are rarely affected. Atypical HFMD presents as a widely distributed rash with varying morphology that makes clinical diagnosis and treatment challenging.2 Our objective is to present atypical cutaneous manifestations of HFMD caused by CA6.

References

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Buttery VW, Kenyon C, Grunewald S, Oberste MS, Nix WA. Atypical presentations of hand, foot, and mouth disease caused by Coxsackievirus A6‑Minnesota, 2014. MMWR Morb Mortal Wkly Rep. 2015;64:805.

Hubiche T, Schuffenecker I, Boralevi F, Léauté‑Labrèze C, Bornebusch L, Chiaverini C, et al. Dermatological spectrum of hand, foot and mouth disease from classical to generalized exanthema. Pediatr Infect Dis J. 2014;33:92-8.

Lott JP, Liu K, Landry ML, Nix WA, Oberste MS, Bolognia J, et al. Atypical hand‑foot‑and‑mouth disease associated with Coxsackievirus A6 infection. J Am Acad Dermatol. 2013;69:736-41.

Kim SJ, Kim JH, Kang JH, Kim DS, Kim KH, Kim KH, et al. Risk factors for neurologic complications of hand, foot and mouth disease in the Republic of Korea, 2009. J Korean Med Sci. 2013;28:120-7.

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Published

2021-11-23

Issue

Section

Letter to the Editor