Clinicoetiological profile and risk assessment of newborn with respiratory distress in a tertiary care centre in South India
DOI:
https://doi.org/10.18203/2349-3291.ijcp20150990Keywords:
Respiratory distress syndrome, Hyaline membrane disease, Meconium aspiration syndrome, Transient tachypnoea of newbornAbstract
Background: Respiratory distress is one of the common manifestation for which newborn seeks admission into NICU. As preterm care is increasing more use of surfactant, CPAP, mechanical ventilation has been seen in managing respiratory distress in newborn. This study has been undertaken to evaluate the various etiological factors, various maternal and neonatal risk factors associated with the development of severe respiratory distress, need for surfactant, CPAP and mechanical ventilation in newborns with respiratory distress and finally to assess the immediate clinical outcome of respiratory distress in newborns in our NICU.
Methods: The present study was conducted in the department of Pediatrics at Alluri Sitarama Raju academy of medical sciences hospital, Eluru, between August 2012 and August 2014 (over a period of 24 months). It is a prospective study.
Results: Out of 100 newborns admitted with respiratory distress, 90% were of respiratory origin. Most common cause was TTNB (32%) but severe distress was contributed maximum by HMD (44.82% of severe distress).
Conclusions: Transient tachypnoea of newborn is the most common cause among newborns with respiratory distress. Majority of newborns develop severe distress immediately after birth. Newborns with gestational age between 28-30 weeks are more prone to develop severe respiratory distress. Newborns weighing <1.5 kg are more prone for development of severe distress. Newborns with one minute APGAR score of <7 are more prone to develop severe distress.
References
Gouyon JB, Ribakovsky C, Ferdynus C, Quantin C, Sagot P, Gouyon B, et al. Severe respiratory disorders in term neonates. Paediatr Perinat Epidemiol. 2008;22(1):22-30.
Kumar A, Bhatnagar V. Respiratory distress in neonates. Indian J Pediatr. 2005;72:425-8.
Angus DC, Linde-Zwirble WT, Clermont G, Griffin MF, Clark RH. Epidemiology of neonatal respiratory failure in the United States. Am J Respir Crit Care Med. 2001;164:1154-60.
Lureti M, Parazzini F, Agarossi A, Bianchi C, Rocchetti M, Bevilacqua G. Risk factors for respiratory distress syndrome in the newborn: a multicentre Italian survey. Acta Obstet Gynecol Scand. 1993;72(5):359-64.
Herbert C. Miller. Respiratory distress syndrome of newborn infants: statistical evaluation of factors possibly affecting survival of premature infants. Pediatrics. 1998;31(4):573-9.
Dani C, Reali MF, Bertin GI, Wiechmann L, Spagnolo A, Tangucci M, et al. Risk factors for the development of respiratory distress syndrome and transient tachypnoea in newborn infants. Eur Respir J. 1999;14(1):155-9.
Nagendra K, Wilson CG, Ravichander B, Sood S, Singh SP. Incidence and etiology of respiratory distress in newborn. Med J Armed Forces India. 1999;55(4):331-3.
Ingemarrson I. Gender aspects of preterm birth. BJOG. 2003;110(Suppl 20):3408.
Rawlings JS, Smith FR. Transient tachypnoea of newborn - an analysis of neonatal and obstetric risk factors. Am J Dis Child. 1984;138(9):869-71.
Narendran V, Donovan FE. Early bubble CPAP and outcomes in ELBW preterm infants. J Perinatol. 2003;23(3):195-9.