DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20213331

Neonatal Leuconostoc lactis meningitis

Senthil Kumar Arumugam, Kaviyarasan Govindharaj

Abstract


Leuconostoc lactis has a low potential for human infection, although serious infections have been documented in immunocompromised persons. The source of this organism is a dairy product. A 3-day old neonate was presented with multifocal clonic seizures who were given formula feed from birth. We isolated Leuconostoc lactis in his Cerebrospinal fluid (CSF), which is resistant to vancomycin. L. lactis meningitis was treated successfully with the injection of ampicillin-sulbactam.


Keywords


Leuconostoc lactis, Meningitis, Neonate

Full Text:

PDF

References


Janow G, Lambert B, Scheiner M, Rosen O, Goldman DL, Soghier L. Leuconostoc septicemia in a preterm neonate on vancomycin therapy: case report and literature review. Am J Perinatol. 2009;26(1):89-91.

Omori R, Fujiwara S, Ishiyama H, Kuroda H, Kohara N. Leuconostoc lactis-A Rare Cause of Bacterial Meningitis in an Immunocompromised Host. Intern Med. 2020;59(22):2935-6.

Principles and practice of infectious diseases, 7th ed. Mandell GL, Bennett JE, Dolin R, Eds. Churchill Livingstone Elsevier, Philadelphia. 2010;2652-3.

Handwerger S, Horowitz H, Coburn K, Kolokathis A, Wormser GP. Infection due to Leuconostoc species: six cases and review. Rev Infect Dis. 1990;12(4):602-10.

Sarmiento-Ortiz EA, Oliveros-Andrade OA, Rojas-Hernandez JP. Endocarditis por Leuconostoc lactis en un lactante: reporte de caso. Rev Fac Med. 2020;68(3):467-70.

Friedland IR, Snipelisky M, Khoosal M. Meningitis in a neonate caused by Leuconostoc spp. J Clin Microbiol. 1990;28(9):2125-6.

Park IS, Walsh CT. D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation. J Biol Chem. 1997;272(14):9210-4.

Rubin LG, Vellozzi E, Shapiro J, Isenberg HD. Infection with vancomycin-resistant "Streptococci" due to Leuconostoc species. J Infect Dis. 1988;157(1):216.