DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20213332

A case report on COVID-19 associated multisystem inflammatory syndrome in children

Sachin Kumar, Deepak Sharma, Khushboo Tongaria, Naman Bansal

Abstract


As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from different parts of India during second wave of infection describing children and adolescents with COVID-19-associated multisystem inflammatory conditions. We describe clinical features and management in children with multisystem inflammatory syndrome children (MIS-C) from the Delhi metropolitan area, which had a high incidence of coronavirus disease 2019 (COVID-19). We report a similar case presenting with persisting fever, rashes, bulbar conjunctivitis, abdominal pain, decreased urine output and shock. Initial reports suggestive of high inflammatory markers, neutrophilic leukocytosis, high D-dimer and found to have COVID-19 IgG antibodies positive in high titre. Managed successfully in PICU with bolos fluids, intravenous antibiotics, steroids and anticoagulation. 


Keywords


COVID-19, MIS, Children

Full Text:

PDF

References


Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M et al. An outbreak of severe Kawasaki-like disease at the Italian epicenter of the SARS-CoV-2 epidemic-an observational cohort study. Lancet. 2020;395:1771-8.

Grimaud M, Starck J, Levy M, Marais C, Chareyre J, Khraiche D et al. Acute myocarditis and multisystem inflammatory emerging disease following SARSCoV-2 infection in critically ill children. Ann Intens Care. 2020;10;69.

Royal College of Pediatrics and Child Health. Guidance-pediatric multisystem inflammatory syndrome temporally associated with COVID-19. Available at: https://www.rcpch.ac.uk/resources. Accessed on 20 Feb 2020.

Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J et al. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663-5.

Tagarro A, Epalza C, Santos M, Sanz-Santaeufemia FJ, Otheo E, Moraleda C et al. Screening and severity of coronavirus disease 2019 (COVID-19) in Children in Madrid, Spain. JAMA Pediatr. 2020.

WHO. 2019. Avaialbe at: WHO/2019-nCoV/Sci_Brief/Multisystem_Syndrome_Children/2020. Accessed on 20 Feb 2020.

Dufort EM, Koumans EH, Chow EJ, Rosenthal EM, Muse A, Rowlands J et al. Multisystem inflammatory syndrome in children in New York State. N Engl J Med. 2020;383:347-58.

Levin M. Childhood multisystem inflammatory syndrome- A new challenge in the pandemic. N Engl J Med. 2020;383:334-46.