A case report on COVID-19 associated multisystem inflammatory syndrome in children

Sachin Kumar; Deepak Sharma; Khushboo Tongaria; Naman Bansal

doi:10.18203/2349-3291.ijcp20213332

Authors

Sachin Kumar Department of Pediatrics, Bansal Hospital, New Friends Colony, New Delhi, India
Deepak Sharma Department of Pediatrics, Kadam Hospital, Bhiwani, Haryana, India
Khushboo Tongaria Department of Obstetrics and Gynaecology, Fortis La-Femme, Greater Kailash, New Delhi, India
Naman Bansal Department of Pediatrics, Bansal Hospital, New Friends Colony, New Delhi, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20213332

Keywords:

COVID-19, MIS, Children

Abstract

As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from different parts of India during second wave of infection describing children and adolescents with COVID-19-associated multisystem inflammatory conditions. We describe clinical features and management in children with multisystem inflammatory syndrome children (MIS-C) from the Delhi metropolitan area, which had a high incidence of coronavirus disease 2019 (COVID-19). We report a similar case presenting with persisting fever, rashes, bulbar conjunctivitis, abdominal pain, decreased urine output and shock. Initial reports suggestive of high inflammatory markers, neutrophilic leukocytosis, high D-dimer and found to have COVID-19 IgG antibodies positive in high titre. Managed successfully in PICU with bolos fluids, intravenous antibiotics, steroids and anticoagulation.

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References

Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M et al. An outbreak of severe Kawasaki-like disease at the Italian epicenter of the SARS-CoV-2 epidemic-an observational cohort study. Lancet. 2020;395:1771-8.

Grimaud M, Starck J, Levy M, Marais C, Chareyre J, Khraiche D et al. Acute myocarditis and multisystem inflammatory emerging disease following SARSCoV-2 infection in critically ill children. Ann Intens Care. 2020;10;69.

Royal College of Pediatrics and Child Health. Guidance-pediatric multisystem inflammatory syndrome temporally associated with COVID-19. Available at: https://www.rcpch.ac.uk/resources. Accessed on 20 Feb 2020.

Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J et al. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663-5.

Tagarro A, Epalza C, Santos M, Sanz-Santaeufemia FJ, Otheo E, Moraleda C et al. Screening and severity of coronavirus disease 2019 (COVID-19) in Children in Madrid, Spain. JAMA Pediatr. 2020.

WHO. 2019. Avaialbe at: WHO/2019-nCoV/Sci_Brief/Multisystem_Syndrome_Children/2020. Accessed on 20 Feb 2020.

Dufort EM, Koumans EH, Chow EJ, Rosenthal EM, Muse A, Rowlands J et al. Multisystem inflammatory syndrome in children in New York State. N Engl J Med. 2020;383:347-58.

Levin M. Childhood multisystem inflammatory syndrome- A new challenge in the pandemic. N Engl J Med. 2020;383:334-46.