DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20212494

COVID-19 triggered systemic lupus erythematosus in a child: a case report

Krishna Prasad Maram, Venkata Rama Rao Paturi, Lalitha Sudha Alla, Murali Krishna Bhagavatula

Abstract


The COVID-19 pandemic has continued to wreak havoc globally during the second wave. Even though it tends to be asymptomatic or cause only a trivial illness in children, it is reported to be associated with a delayed hyper-inflammatory response syndrome resulting in multi-organ dysfunction in children. It is possible that through unknown mechanisms, it could also result in triggering of other auto-immune disorders. We report a case of pediatric systemic lupus erythematosus (SLE) with lupus nephritis suspected to be triggered by SARS-CoV-2 virus which is not reported in the literature so far.


Keywords


COVID-19, Systemic lupus erythematosus, Auto-immunity

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References


Team NCPERE. Vital surveillances: the epidemiologicalcharacteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) China. China CDC Weekly. 2020;2:113-22.

Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H et al. Clinical course and outcomes of criticallyill patients with SARS-CoV-2 pneumonia inWuhan, China: a single-centered, retrospective, observational study. Lancet Resp Med. 2020;8:475-81.

Guo CX, He L, Yin JY. Epidemiological and clinical features of pediatric COVID-19. BMC Med. 2020;18:250.

Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF et al. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med. 2020;1-13.

Bonometti R, Sacchi MC, Stobbione P, Lauritano EC, Tamiazzo S, Marchegiani A et al. The first case of systemic lupus erythematosus (SLE) triggered by COVID-19 infection. Eur Rev Med Pharmacol Sci. 2020;24(18):9695-7.