Coronavirus disease 2019 in neonates
Keywords:Neonates, COVID-19, SARS-CoV-2
Coronavirus disease 2019 (COVID-19) as a global pandemic has become a major burden especially in the health care system and economy. COVID-19 has clinical presentations ranging from remain asymptomatic to severe acute respiratory distress syndrome (ARDS) and death. All age groups are susceptible to this virus, but it seems that children with COVID-19 have milder symptoms than adults. Neonates, however, have been reported to have more severe cases compared to older children. There is also a possibility of vertical transmission from mothers to their neonates which could not be ignored. This review provides current knowledge of COVID-19 in neonates.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. New Engl J Med. 2020.
World Health Organization. COVID-19 weekly epidemiological update, 7 March 2021. Available at https://www.who.int/docs/default-source/coronaviruse/situation-reports/20210309_weekly_epi_update_30.pdf?sfvrsn=4e7da248_8&download=true. Accessed on 12 March 2021.
Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of covid-19 among children in China. Pediatrics 2020;145(6):e20200702.
Gale C, Quigley MA, Placzek A, Knight M, Ladhani S, Draper ES, et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child Adolesc Heal. 2021;5(2):113-21.
Yuki K, Fujiogi M, Koutsogiannaki S. Covid-19 pathophysiology: a review. Clinical Immunol. 2020;215:108427.
Kallem VR, Sharma D. COVID 19 in neonates. J Matern Fetal Neonatal Med 2020.
Ouassou H, Kharchoufa L, Bouhrim M, Daoudi NE, Imtara H, Bencheikh N, et al. The pathogenesis of coronavirus disease 2019 (covid-19): evaluation and prevention. J Immunol Res. 2020;1357983.
Cevik M, Kuppalli K, Kindrachuk J, Peiris M. Virology, transmission, and pathogenesis of SARS-CoV-2. Bio Med J. 2020;371:m3862.
Dong L, Tian J, He S, Zhu C, Wang J, Liu C, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. J Am Med Assoc 2020;323(18):1846-8.
Zeng H, Xu C, Fan J, Tang Y, Deng Q, Zhang W, et al. Antibodies in infants born to mothers with COVID-19 pneumonia. J Am Med Assoc. 2020;323(18):1848-9.
Wu YT, Liu J, Xu JJ, Chen YF, Yang W, Chen Y, et al. Neonatal outcome in 29 pregnant women with covid-19: a retrospective study in Wuhan, China. PLoS Med 2020;17(7):e1003195.
Kalyanasundaram S, Krishnamurthy K, Sridhar A, Narayanan VK, Santosh ABR,Rahman S. Novel corona virus pandemic and neonatal care: it’s to early to speculate on impact. SN Compr Clin Med 2020;2:1412-8.
Zimmermann P, Curtis N. Covid-19 in children, pregnancy and neonates: a review of epidemiologic and clinical features. Pediatr Infect Dis J 2020;39:469-77.
Mimouni F, Lakshminrusimha S, Pearlman SA, Raju T, Gallagher PG, Mendlovic J. Perinatal aspects on the covid-19 pandemic: a practical resource for perinatal-neonatal specialists. J Perinatol 2020;40:820-6.
Trevisanuto D, Cavallin F, Cavicchiolo ME, Borellini M, Calgaro S, Baraldi E. Coronavirus infection in neonates: a systematic review. Arch Dis Child Fetal Neonatal Ed 2020;0:F1-6.
De Rose DU, Piersigilli F, Ronchetti MP, Santisi A, Bersani I, Dotta A, et al. Novel coronavirus disease (COVID-19) in newborns and infants: what we know so far. Ital J Pediatr 2020;46:56.
Nayak M, Panda S, Pradhan JB, Mohakud NK. Coronavirus disease 2019 in neonates – what is known and what needs to be known. Cureus 2020;12(8):e10171.
Amatya S, Corr TE, Gandhi CK, Glass KM, Kresch MJ, Mujsce DJ, et al. Management of newborns exposed to mothers with confirmed of suspected covid-19. J Perinatol 2020;40:987-96.
Sankaran D, Nakra N, Cheema R, Blumberg D, Lakshminrusimha S. Perinatal SARS-CoV-2 infection and neonatal covid-19: a 2021 update. Neo Reviews 2021;22(5)10.
Liu W, Wang J, Li W, Zhou Z, Liu S, Rong Z. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med 2020;14:193-8.
Salvatore CM, Han JY, Acker KP, Tiwari P, Jin J, Brandler, et al. Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study. Lancet Child Adolesc Health 2020;4:721-7.
Stanojevic M. Are covid-19-positive mothers dangerous for their term and well newborn babies? Is there an answer? J Perinat Med 2020;48(5):441-5.
Shalish W, Lakshminrusimha S, Manzoni P, Keszler M, Sant’Anna GM. COVID-19 and neonatal respiratory care: current evidence and practical approach. Am J Perinatol 2020;37(8):780-91.
Davanzo R, Moro G, Sandri F, Agosti M, Moretti C, Mosca F. Breastfeeding and coronavirus disease-2019: Ad interim indications of the Italian society of neonatology endorsed by the Union of European Neonatal & Perinatal Societies. Matern Child Nutr 2020;16:e13010.