DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20170048

A study on common pathogens associated with nosocomial infections and their antibiotic sensitivity

Varsha Suresh Ahirrao, Anupama Mauskar, Ravi T.

Abstract


Background: S. aureus, coagulase negative staphylococci, enterococci, a variety of gram-negative bacilli, and Candida spp. are responsible for the vast majority of infections. Coagulase negative staphylococcal infections have increased dramatically in past 2 decades, almost entirely because of increase in the frequency of blood stream infections caused by these organisms.

Methods: Appropriate microbiological samples were taken from the site of infection from all the patients included in the study. Whenever necessary, required serological examinations are sent.

Results: Of 30 episodes of nosocomial infections from which any pathogen was isolated, three episodes were polymicrobial. Gram-negative organisms were more frequently (76.67%) isolated than gram-positive organisms (20%), and fungi (3.33%).

Conclusions: Almost all gram-negative bacteria showed 100% sensitivity to Imipenem. Pseudomonas isolates showed sensitivity of 100% to Imipenem, 83.33% to Piperacillin+Tazobactum. Klebsiella showed sensitivity of 83.33% to Ciprofloxacin and Amikacin.


Keywords


Antibiotic Sensitivity, Nosocomial infection, Pathogens

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References


Scott KF, Sharon FW, Robert AW. Magnitude and prevention of nosocomial infection in the Intensive care unit. Infec Dis clin North Am. 1997;11:479-96.

Ananthnarayan R, Paniker CKJ. Pseudomonas. Textbook of Microbiology; 4th ed, Orient Longman; 1990:310-313.

Tullu MS, Deshmukh CT, Baveja SM. Bacterial profile and antimicrobial suspectibility pattern in catheter related nosocomial infection. J Postgrad Med. 1998;44(1):7-13.

Marcelo L, Werther B, Carvalho Eduardo S carvalho II; Eduardo AS, medeivos I, II: Nosocomial Infection in a pediatric intensive care clinic in a developing country. Braz J Infect DIS. 2003;7(6):1407-17.

Urrea M, Pons M, Latorrec SM, Palomeq A. Prospective incidence study of nosocomial infections in a pediatric intensive care unit. Pediatr Infect Dis J. 2003;22(6):490-4.

Richards MJ, Edwards JR, Culver DH, Gayness RP. Nosocomial infections in pediatric intensive care unit in the United States. National Nosocomial Infection Surveillance System. Pediatr. 1999;103(4):e39.

Deep A, Ghildiyal R, Kandian S, Shinkre N. Clinical and microbiological profile of nosocomial infections in pediatric intensive care unit. Indian Pediatr. 2004;41:1238-46.

Sleigh JD, Timbury MC. Notes on Medical Bacteriology. 2nd edition. 1986;314-318.

Bowen-Jones J, Wesley A, Ende J. Nosocmial colonization and infection In a pediatric respiratory intensive care unit. S Afr Med J. 1992;14:949-51.

Figuerosa A. Prevalence of nosocomial infections in children:survey of 25 Hospitals in Mexico. Salud Publica de Mexico 41st suppl; 1999;518-25.

Bueno Cavanillas A, Rodriguez D. Influence of nosocomial infection on mortality rate in an intensive care unit. Critical Care Medicine (United States). 1994:22(1):55-60.

Dinkel RH. A survey of nosocomial infections and their influence on hospital mortality rates. J Hospital Infect Eng. 1994;28(4):297-304.

Hampton AA, Schertz RJ. Vascular access. Infections in hospitalized patients. Surgical Clinics of North America. 1988;68:57-71.

Garner IS, Jarvis WR, Emori TG. CDC Definition for nosocomial infections. AMJ Infec Control. 1988;16;128.

Stamm WF. Catheter associated urinary tract infections. Epidemiology, pathogenesis and prevention. Am J Med. 1991;655-715.