Congenital hypofibrinogenemia: a case report


  • Pandala Paramesh Department of Pediatrics, Niloufer Hospital, Red Hills, Hyderabad, Telangana
  • Usha Rani Thota Department of Pediatrics, Niloufer Hospital, Red Hills, Hyderabad, Telangana
  • Rakesh Kotha Department of Neonatology, Niloufer Hospital, Red Hills, Hyderabad, Telangana



Fibrinogen, Bleeding diathesis, Congenital hypofibrinogenemia and children


Fibrinogen disorders are rare bleeding disorders. Fibrinogen is also called factor I which is involved in last step of coagulation cascade. Congenital hypofibrinogenemia is usually caused by mutation of FIB (fibrinogen-binding protein) gene. These disorders should be suspected when Thrombin time is prolonged in well look child with history of bleeding manifestations. We are describing a female child who is having pallor with history of recurrent ecchymosis and minor post traumatic bleeding. Based on coagulation screening profile, we made the diagnosis of hypofibrinogenemia.

Author Biography

Rakesh Kotha, Department of Neonatology, Niloufer Hospital, Red Hills, Hyderabad, Telangana

asst professor niloufer MD DM


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