Trend of multi drug resistant typhoid in South India

Authors

  • Karthik Prabhu Ramaraj Department of Pediatrics, Kanchi Kamakoti Childs Trust Hospital, Nungambakkam, Chennai, India
  • Ganesh R Department of Pediatrics, Kanchi Kamakoti Childs Trust Hospital, Nungambakkam, Chennai, India
  • Lalitha Janakiraman Department of Pediatrics, Kanchi Kamakoti Childs Trust Hospital, Nungambakkam, Chennai, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20160183

Abstract

Multidrug-resistant typhoid fever (MDRTF) is defined as typhoid fever caused by S. Typhi strains which are resistant to all the three first-line recommended drugs for treatment, i.e., chloramphenicol, ampicillin, and co-trimoxazole (TMP-SMX). A recent multi-centric study conducted across five Asian countries (China, India, Indonesia, Pakistan, and Vietnam) that are endemic for typhoid reported the prevalence of multidrug-resistant Salmonella typhi strains ranging from 7% to 65%.

References

Ochiai RL, Acosta CJ, Danovaro-Holliday MC, Baiqing D, Bhattacharya SK, Agtini MD, et al. A study of typhoid fever in five Asian countries: disease burden and implications for controls. Bull World Health Organ. 2008;86(4):260-8.

Gupta V, Kaur J, Kaistha N. Re-emerging chloramphenicol sensitivity and emerging low level ciprofloxacin resistance among Salmonella enterica serotype typhi isolates in North India. Trop Doct. 2009;39(1):28-30.

Prajapati B, Rai GK, Rai SK, Upreti HC, Thapa M, Singh G, et al. Prevalence of Salmonella typhi and paratyphi infection in children: a hospital based study. Nepal Med Coll J. 2008;10(4):238-41.

Pitzer VE, Bowles CC, Baker S, Kang G, Balaji V, Farrar JJ, et al. Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study. PLoSNegl Trop Dis. 2014;8(1):e2642.

Madhulika U, Harish BN, Parija SC. Current pattern in antimicrobial susceptibility of Salmonella Typhi isolates in Pondicherry. Indian J Med Res. 2004;120(2):111-4.

Krishnan P, Stalin M, Balasubramanian S. Changing trends in antimicrobial resistance of Salmonella entericaserovartyphi and salmonella entericaserovarparatyphi A in Chennai. Indian J Pathol Microbiol. 2009;52(4):505-8.

Choudhary A, Gopalakrishnan R, Nambi PS, Ramasubramanian V, Ghafur KA, Thirunarayan MA. Antimicrobial susceptibility of Salmonella entericaserovars in a tertiary care hospital in southern India. Indian J Med Res. 2013;137(4):800-2.

Krishnan P, Stalin M, Balasubramanian S. Changing trends in antimicrobial resistance of Salmonella enterica serovar typhi and salmonella enterica serovar typhi A in Chennai. Indian J Pathol Microbiol. 2009;52(4):505-8.

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Published

2016-12-31