Trend of multi drug resistant typhoid in South India
Multidrug-resistant typhoid fever (MDRTF) is defined as typhoid fever caused by S. Typhi strains which are resistant to all the three first-line recommended drugs for treatment, i.e., chloramphenicol, ampicillin, and co-trimoxazole (TMP-SMX). A recent multi-centric study conducted across five Asian countries (China, India, Indonesia, Pakistan, and Vietnam) that are endemic for typhoid reported the prevalence of multidrug-resistant Salmonella typhi strains ranging from 7% to 65%.
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