Dyke Davidoff Masson syndrome: a rare cause of cerebral hemiatrophy in 11 months old

Amit Vatkar, Ipsita Vashishtha, Vinaykumar P. Hedaginal, B. Revanth Sai Madhav


Dyke-Davidoff-Masson syndrome (DDMS) is an uncommon condition, characterized radiologically by cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses, of unknown frequency resulting from brain injury due to large no of causes; especially in early life. Mostly presents early in life with seizures, learning difficulty, contralateral hemiparesis and facial symmetry. Here we present a case of 11 months old female child with developmental delay, visual abnormality, microcephaly and spastic hemiplegia. CT-brain done which was suggestive of infantile type of cerebral hemiatrophy or DDMS.


Dyke-Davidoff-Masson syndrome, Hemiatrophy, Spastic hemiplegia

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Sharma S, Goyal l, Negi A, Sood RG, Jhobta A, Surya M. Dyke-Davidoff-Masson Syndrome. Ind J Radiol Imag. 2006;16:165-6.

Hageman G, Gooskens RH, Willemse J. A cerebral cause of arthrogryposis: Unilateral cerebral hypoplasia. Clin Neurol Neurosurg. 1985;87:119-22.

Goyal J, Shah V, Rao S, Jindal N. Dyke–Davidoff–Masson syndrome in children. Internet J Pediatr Neonatol. 2009;10:101-7.

Dyke CG, Davidoff LM, Masson CB. Cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses. Surg Gynecol Obstet. 1933;57:588-600.

Behera MR, Patnaik S, Mohanty AK. Dyke-Davidoff-Masson syndrome. J of neurosciences in rural practice. 2012;3(3):411-3.

Graham A, Molnar Z. Development of the Nervous system. In: Standring S, editor. Gray's Anatomy. 40th ed. London, Churchill Livingstone: Elsevier. 2008;385.

Pendse NA, Bapna P, Menghani V, Diwan A. Dyke-Davidoff-Masson Syndrome. Indian J Pediatr. 2004;71:943.

Parker CE, Harris N, Mavalwala J. Dyke-Davidoff-Masson Syndrome: Five case studies and deductions from dermatoglyphics. Clin Pediatr. 1972;11:28.

Rao KC. Degenerative diseases and hydrocephalus. In: Lee SH, Rao KC, Zimmerman RA, editors. Cranial MRI and CT. New York: McGraw-Hill. 1999;212–4.

Zilkha A. CT of Cerebral hemiatrophy. Am J Roentgenol. 1980;135:259-62.