Vitamin D levels in children with bronchial asthma


  • Kaisar R. Wani Department of Pediatrics, SKIMS Soura, Srinagar, Jammu and Kashmir, India
  • Reyaz A. Malik Malik Department of Pediatrics, SKIMS MCH, Srinagar, Jammu and Kashmir, India
  • Asif Ahmed Department of Pediatrics, SKIMS MCH, Srinagar, Jammu and Kashmir, India



Vitamin D deficiency, Bronchial asthma, Chronic inflammatory disorder


Background: Bronchial asthma is a common chronic inflammatory disorder of the airways in childhood. Vitamin D, initially described as a vitamin that regulated calcium homeostasis, has also been shown to exert important antimicrobial effects and is also a potent immune system regulator having a potential role in various allergic diseases. The main objective of this study was to look the levels of vitamin D in children with bronchial asthma and to study the co relationship between vitamin D levels and severity of asthma.

Methods: This study included 80 (40 asthmatic children and 40 healthy controls) children aged between 4 and 15 year. Serum vitamin D levels where determined and compared between the two groups. The association between vitamin D levels and severity of asthma was studied in the asthmatic children.

Results: Among 40 asthmatic children the mean serum vitamin D level was 16.6±11.56 ng/ml, while as the mean vitamin D levels in healthy control subjects was 24.225±2.764 ng/ml and the difference between the two groups was statistically significant (p=0.001). Vitamin D deficiency was highly prevalent in asthmatic patients and there was a direct and a significant relationship between serum vitamin D levels and severity of asthma.

Conclusion: In this study, vitamin D levels were considerably lower in children with asthma than in healthy children. Also, in this study vitamin D deficient asthma patients have more severe asthma than the patients who have sufficient vitamin D levels.

Author Biographies

Reyaz A. Malik Malik, Department of Pediatrics, SKIMS MCH, Srinagar, Jammu and Kashmir, India

Associate Professor

Asif Ahmed, Department of Pediatrics, SKIMS MCH, Srinagar, Jammu and Kashmir, India

Lecturer , Department of Pediatrics, SKIMS Medical College , Srinagar, J&K


From the Global strategy for asthma Management and prevention. Global initiative for Asthma (GINA) 2020. Available at: Accessed on 20 August 2020.

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