Ohtahara syndrome progressing to West syndrome


  • Tapan Patel Department of Paediatrics, Medical College, Baroda, Gujarat, India
  • Shivani Patel Department of Paediatrics, Medical College, Baroda, Gujarat, India




Ohtahara syndrome, West syndrome, Breakthrough seizures, Rare disease


West syndrome is a severe epilepsy syndrome composed of the triad of infantile spasms, hypsarrhythmia on electroencephalography (EEG) and mental retardation. It is sometimes due to the progression of a rare and fatal condition called early infantile epileptic encephalopathy (Ohtahara syndrome). Here we describe the case of a 3 year old male, who is a known case of West syndrome, presenting with recurrent breakthrough convulsions.


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Case Reports