Assessment of quality of life in asthma patients in 5 to 18 years of children
DOI:
https://doi.org/10.18203/2349-3291.ijcp20204549Keywords:
Paediatric asthma, Patient and parent related outcome, QOLAbstract
Background: Asthma is a common cause of morbidity and mortality with prevalence of 300 million in world. The QOL of asthmatic patients cannot be determined only on the basis of the severity of the disease, but requires a measurement of personal perception. This study was conducted with the aim to assess and compare the QOL using PedsQl scale in asthma patients between 5 to 18 years of age with different demographic and clinical variables.
Methods: This was a cross-sectional observational study conducted at respiratory clinic in tertiary hospital, Rewa from October 2017 to June 2019. A total number of 150 asthmatic patients and their parents participated. Asthmatic patients (N=150) and their parents, presenting to asthma clinic of Gandhi Memorial Hospital, Rewa (after applying inclusion-exclusion criteria) were assessed for QOL using PedsQl scale 3.0. Statistical analysis was performed by SPSS version 20. Test of significance by student T-test and one way ANOVA.
Results: The QOL is severely hampered by asthma with mean of 59 in intermittent asthma, 51 in mild, 44.74 in moderate and 40 in severe persistent asthma, significant p value of <0.05. Younger age, level of asthma control and severity were significantly related to QOL with p value of <0.05. Sex, socioeconomic status, were insignificantly related.
Conclusions: QOL is impaired as the grading of asthma increases. Impairment of Quality of life are mostly associated with low level of asthma control, poly-therapy and frequent night attacks.
References
India state-level Disease Burden Initiative CRD Collaborators. The Burden of chronic respiratory diseases and their heterogeneity across the states of India. Lancet. 2018;6(12):E1363-74,
Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention 2014. Available at: http://www.ginasthma.org.
Masoli M, Fabian D, Holt S, Beasley R, Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy. 2004;59(5):469-78.
Upton P, Lawford J, Eiser C. Parent-child agreement across child health-related quality of life instruments: a review of the literature. Qual Life Res. 2008;17:895-913.
World Health Organization. Constitution of the World Health Organization basic document. Geneva, Switzerland: World Health Organization; 1948. Available at: https://www.who.int/ governance/eb/who_constitution_en.pdf.
Singh T, Sharma S, Nagesh S. Socio-economic status scales updated for 2017. Int J Res Med Sci. 2017;5(7):3264.
2000 CDC growth charts (boys) for the United States. Hyattsville, Md: Public Health Service, Centers for Disease Control and Prevention, National Center for Health Statistics. DHHS publication; 2002:190.
2000 CDC growth charts (girls) for the United States. Hyattsville, Md: Public Health Service, Centers for Disease Control and Prevention, National Center for Health Statistics. DHHS publication; 2002:190.
Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention 2018. Available at: http://www. ginasthma.org.
El Gendi S, Mostafa S, Walli M, Hassan O, ElAwady M, Omar D. Assessment of health-related quality of life in asthmatic children and their caregivers. Int J Med Sci Public Health. 2017;6(4):1.
Abdel Hai R, Taher E, Abdel Fattah M. Assessing validity of the adapted Arabic paediatric asthma quality of life questionnaire among Egyptian children with asthma. East Mediterr Health J. 2010;6(3):274-80.
Ziora D, Madaj A, Wieckowka E, Ziora K, Kozielski K. Correlation of spirometric parameters taken at a single examination with the quality of life in children with stable asthma. J Physiol Pharmacol. 2007;58(5):801-9.