Clinical study of recurrent respiratory tract illness among pediatric patients

K. Rajashekar Rao; Sheetal S. Gandhi; Prashant R. Kokiwar

doi:10.18203/2349-3291.ijcp20160161

Authors

K. Rajashekar Rao Professor, Department of Pediatrics, Malla Reddy Medical College for Women, Suraram, Hyderabad, Telangana, India
Sheetal S. Gandhi Professor, Department of Pediatrics, Malla Reddy Medical College for Women, Suraram, Hyderabad, Telangana, India
Prashant R. Kokiwar Professor & HOD, Department of Community Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20160161

Keywords:

Clinical study, Recurrent respiratory tract illness, Pediatric patients

Abstract

Background: Pediatric respiratory tract illness is one of the most common reasons for physician visits and hospitalization and is associated with significant morbidity and mortality. Respiratory illnesses are common and frequent and present on EOF the major complaints in children and adolescents. Respiratory illness, mainly involving the upper airways, are common in children and their recurrence constitutes a demanding challenge for the paediatricians. There are many children suffering from so called recurrent respiratory illness (RRI). The objective was to study recurrent respiratory tract illness among pediatric patients

Methods: A Hospital based cross sectional study was carried out from March 2013 to February 2014 among 99 children aged between 6 months to 5 years of age at Kamineni Hospital, LB Nagar, Hyderabad, Telangana, India. Informed consent and approval of institutional ethical committee was taken prior to the study. Children with age less than 6 months and more than 5 years, children with congenital heart disease, children with cerebral palsy, and children with proven immunodeficiency disorder were excluded from the study. All parents were asked a detailed history of the child. Complete clinical examination was done for all children. They were subjected to blood investigations.

Results: Elevation of serum IgE levels was more (78.04%) in not exclusively breast fed as compared to those who were exclusively breast feed (27.58%) with p value of 0-0001. Out of 48 children with elevated serum IgE levels, 46 (53.48%) were born at term gestation and only 2 (15.38%) were preterm. This was statistically significant with p value of 0.01. Serum IgE levels were significantly elevated in 85% of children with family history of recurrent respiratory tract illnesses with p value of 0.001. 50% children with elevated eosinophils had elevated serum IgE levels with p value 0.93 which was not significant.

Conclusions: There was a significant role of family history of recurrent respiratory tract illness in children with elevated serum IgE levels. Serum IgE levels were elevated in 50% of the children with increased Eosinophils, but there was no significant correlation of percentage of Eosinophils and serum IgE levels.

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References

Bellanti JA. Recurrent respiratory tract infections in pediatric patients. Drugs. 1997;54(Suppl 1):1-4.

Graham NM. The epidemiology of acute respiratory infections in children and adults: a global perspective. Epidemiol Rev. 1990;12:149-78.

Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective, cohort study. J Infect Dis. 1989;160(1):83-94.

Subramanyam L. Recurrent respiratory infections- An approach. IJPP. 2012;14(3):245-7.

Beard LJ, Maxwell GM, Thong YH. Immunocompetence of children with frequent respiratory infections. Arch Dis Child. 1981;56(2):101-5.

Issacs D, Clarke JR, Tyrrell DA, Valman HB. Selective infections of lower respiratory tract by respiratory viruses in children with recurrent respiratory tract infections. Br Med J (Clin Res Ed). 1982;184(6331):1746-8.

Venuta A, Spano C, Laudizi L, Bettelli F, Beverelli A, Turchetto E. Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections. J Int Med Res. 1996;24(4):325-30.

Chapelin C, Coste A, Reinert P, Boucherat M, Millepied MC, Poron F, et al. Incidence of primary ciliary dyskinesia in children with recurrent respiratory diseases. Ann Otol Rhinol Laryngol. 1997;106(10 Pt 1):854-8.

Giraudi V, Riganti C, Torales MR, Sedola H, Gaddi E. Upper respiratory infections in children: response to endonasal administration of IGA. Int J Pediatr Otorhinolaryngol. 1997;39(2):103-10.

Hewson-Bower B, Drummond PD. Psychological treatment for recurrent symptoms of colds and flu in children. J Psychosom Res. 2001;51(1):369-77.

Couriel J. Assessment of the child with recurrent chest infections. Br Med Bull. 2002;61:115-32.

Siltanen M, Wehkalampi K, Hovi P, Eriksson JG, Strange-Karlsson S, Jarvenpaa AL et al. Preterm birth reduces the incidence of atopy in adulthood. J Allergy Clin Immunol. 2011;127(4):935-42.

Croner S, Kjellman NI, Eriksson B, Roth A. IgE screening in 1701 newborn infants and the development of atopic disease during infancy. Arch Dis Child. 1982;57(5):364-8.

Ebrahim R, Hassan E, Hossein A, Vajihe C, Armin R. Evaluation of high sensitivity C reactive protein in acute asthma. Tanaffos. 2012;11(1):32-7.

Rusconi F, Patria MF, Cislaghi GU, Sideri S, Gagliardi L. Total serum IgE and outcome in infants with recurrent wheezing. Arch Dis Child. 2001;85(1):23-5.

Stempel DA, Clyde WA Jr, Henderson FW, Collier AM. Serum IgE levels and the clinical expression of respiratory illnesses. J Pediatr. 1980;97(2):185-90.

Dellepiane RM, Pavesi P, Patria MF, Laicini E, Di Landro G, Pietrogrande MC. Atopy in preschool Italian children with recurrent respiratory infections. Pediatr Med Chir. 2009;31(4):161-4.